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rdf:type |
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lifeskim:mentions |
umls-concept:C0007600,
umls-concept:C0014597,
umls-concept:C0016026,
umls-concept:C0017262,
umls-concept:C0033572,
umls-concept:C0185117,
umls-concept:C0205225,
umls-concept:C0205263,
umls-concept:C0205307,
umls-concept:C0389877,
umls-concept:C0600139,
umls-concept:C1518174,
umls-concept:C2911684
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pubmed:issue |
4
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pubmed:dateCreated |
1999-12-22
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pubmed:abstractText |
It has been determined that prostate cancer cells overexpress the matrix metalloprotease matrilysin (MMP-7), but the factors regulating this expression have not been identified. Fibroblast growth factors (FGF), which are expressed in the prostate, might participate in paracrine regulation of matrilysin expression by prostate cancer cells.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Culture Media, Conditioned,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Precursors,
http://linkedlifedata.com/resource/pubmed/chemical/Fibroblast Growth Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Metalloendopeptidases,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Fibroblast Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/promatrilysin
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0270-4137
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 1999 Wiley-Liss, Inc.
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
215-23
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10544294-Carcinoma,
pubmed-meshheading:10544294-Cell Line,
pubmed-meshheading:10544294-Culture Media, Conditioned,
pubmed-meshheading:10544294-Dose-Response Relationship, Drug,
pubmed-meshheading:10544294-Enzyme Inhibitors,
pubmed-meshheading:10544294-Enzyme Precursors,
pubmed-meshheading:10544294-Epithelial Cells,
pubmed-meshheading:10544294-Fibroblast Growth Factors,
pubmed-meshheading:10544294-Fibroblasts,
pubmed-meshheading:10544294-Humans,
pubmed-meshheading:10544294-Male,
pubmed-meshheading:10544294-Metalloendopeptidases,
pubmed-meshheading:10544294-Prostate,
pubmed-meshheading:10544294-Prostatic Neoplasms,
pubmed-meshheading:10544294-RNA, Messenger,
pubmed-meshheading:10544294-Receptors, Fibroblast Growth Factor,
pubmed-meshheading:10544294-Recombinant Proteins,
pubmed-meshheading:10544294-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
1999
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pubmed:articleTitle |
Promatrilysin expression is induced by fibroblast growth factors in the prostatic carcinoma cell line LNCaP but not in normal primary prostate epithelial cells.
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pubmed:affiliation |
Department of Radiation Oncology, University of Arizona Health Sciences Center, Tucson, Arizona 85724-5024, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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