Linked Life Data

10542148

Source:http://linkedlifedata.com/resource/pubmed/id/10542148

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5441
pubmed:dateCreated
1999-11-24
pubmed:abstractText
Posttranscriptional gene silencing (PTGS) is a nucleotide sequence-specific defense mechanism that can target both cellular and viral mRNAs. Here, three types of transgene-induced PTGS and one example of virus-induced PTGS were analyzed in plants. In each case, antisense RNA complementary to the targeted mRNA was detected. These RNA molecules were of a uniform length, estimated at 25 nucleotides, and their accumulation required either transgene sense transcription or RNA virus replication. Thus, the 25-nucleotide antisense RNA is likely synthesized from an RNA template and may represent the specificity determinant of PTGS.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0036-8075
pubmed:author
pubmed:issnType
Print
pubmed:day
29
pubmed:volume
286
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
950-2
pubmed:dateRevised
2007-3-19
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
A species of small antisense RNA in posttranscriptional gene silencing in plants.
pubmed:affiliation
Sainsbury Laboratory, John Innes Centre, Colney Lane, Norwich NR4 7UH, UK.
pubmed:publicationType
Journal Article, Comment, Research Support, Non-U.S. Gov't