Linked Life Data

10541747

Source:http://linkedlifedata.com/resource/pubmed/id/10541747

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1999-11-23
pubmed:abstractText
The tonically active neurons in the monkey striatum respond to stimuli presented during the performance of appetitively motivated behavior. To test whether these neurons are selectively responsive to the appetitive properties of stimuli, we studied their responsiveness to three different stimuli presented in an unsignalled manner to monkeys not performing any behavioral tasks: (1) an appetitive liquid, eliciting licking movements; (2) an aversive air puff directed towards the face, eliciting eyelid closure and facial movements; (3) a neutral sound, eliciting no overt behavioral reactions. The great majority of the tonic striatal neurons tested in two monkeys showed pronounced responses to the delivery of liquid (338 of 388 neurons, 87%) or the onset of the air puff stimulus (168 of 204, 82%). In contrast, few neurons (15 of 68, 22%) were modulated by the sound. The majority (80%) of the neurons tested with appetitive and aversive stimuli (n=189) responded to both types of stimulus. The characteristics of neuronal responses to the liquid were generally not similar to those described for the air puff in terms of response pattern and response duration. This suggests the existence of differences in the encoding of the affective significance of stimuli. It is concluded that tonic striatal neurons might function to differentiate stimuli that are important to the animal from those that are not, regardless of the specific motivational attributes of relevant stimuli.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0014-4819
pubmed:author
pubmed:issnType
Print
pubmed:volume
128
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
531-4
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Tonically active neurons in the monkey striatum do not preferentially respond to appetitive stimuli.
pubmed:affiliation
Laboratoire de Neurobiologie Cellulaire et Fonctionnelle, CNRS, 31 Chemin Joseph Aiguier, 13402 Marseille cedex 20, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't