Linked Life Data

10535779

Source:http://linkedlifedata.com/resource/pubmed/id/10535779

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1999-11-19
pubmed:abstractText
Most studies find that associations between mortality and either body mass index or weight change are U-shaped. Previous studies, however, have not considered independent effects of weight level and weight change while also controlling for confounding by diseases leading to weight change. We used follow-up data on average 10-year total mortality from a Danish population of 15,113 men and women, who had their weight measured at about 5-year intervals. We obtained information on preexisting disease at surveys and by linkage to hospital discharge registers. We defined subclinical disease as incident disease or death during the first 4 years of follow-up. We decomposed the mortality risk associated with weight change into a static effect, corresponding to the difference in mortality at stable weight at the initial and attained weight, and a dynamic effect, estimated as the difference between mortality after weight change and mortality at stable weight at the attained weight. Both weight level and weight change had independent effects on total mortality, with both these associations being U-shaped. Adjustment for smoking and the exclusion of subjects with preexisting and subclinical disease did not alter the associations.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1044-3983
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
671-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Independent effects of stable and changing body weight on total mortality.
pubmed:affiliation
Copenhagen Centre for Prospective Population Studies, Denmark.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't