Source:http://linkedlifedata.com/resource/pubmed/id/10534728
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2000-1-12
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pubmed:abstractText |
Cervical shedding of cytomegalovirus (CMV) is important in transmission of CMV to exposed sexual partners and neonates. We evaluated prevalence and correlates of CMV DNA shedding in cervical secretions from a large cohort of HIV-1-seropositive women. Using polymerase chain reaction (PCR) assays, CMV DNA was detected in 183 (59%) cervical swab samples from 311 women. Cervical shedding of CMV DNA was significantly associated with shedding of HIV-1 DNA (odds ratio 1.8; 95% confidence interval 1.1-2.8). CMV shedding was also more frequent in women with Neisseria gonorrhoeae and Trichomonas vaginalis infections, but these associations were not statistically significant. Cervical shedding of CMV in HIV-1-infected women is very frequent and may reflect higher risk of transmission to sexual partners and neonates than previously appreciated.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0146-6615
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 1999 Wiley-Liss, Inc.
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pubmed:issnType |
Print
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
469-73
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10534728-Adolescent,
pubmed-meshheading:10534728-Adult,
pubmed-meshheading:10534728-Cervix Uteri,
pubmed-meshheading:10534728-Cohort Studies,
pubmed-meshheading:10534728-Cytomegalovirus,
pubmed-meshheading:10534728-Cytomegalovirus Infections,
pubmed-meshheading:10534728-DNA, Viral,
pubmed-meshheading:10534728-Female,
pubmed-meshheading:10534728-HIV Infections,
pubmed-meshheading:10534728-HIV-1,
pubmed-meshheading:10534728-Humans,
pubmed-meshheading:10534728-Middle Aged,
pubmed-meshheading:10534728-Polymerase Chain Reaction,
pubmed-meshheading:10534728-Virus Shedding
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pubmed:year |
1999
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pubmed:articleTitle |
Cervical shedding of cytomegalovirus in human immunodeficiency virus type 1-infected women.
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pubmed:affiliation |
Department of Epidemiology, University of Washington, Seattle, Washington 98195, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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