|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0003250,
umls-concept:C0020855,
umls-concept:C0086418,
umls-concept:C0220825,
umls-concept:C0277784,
umls-concept:C0441833,
umls-concept:C0678946,
umls-concept:C1280500,
umls-concept:C1533691,
umls-concept:C1999270,
umls-concept:C2754949
|
|
pubmed:issue |
9
|
|
pubmed:dateCreated |
1999-11-5
|
|
pubmed:abstractText |
The D immunoprophylaxis program has successfully reduced the incidence of Rh hemolytic disease of the newborn (HDN), but it has also reduced the availability of plasma-derived polyclonal anti-D, which constitutes the current therapeutic product. Human monoclonal anti-D from hybridoma cell lines may be an acceptable alternative, and clinical efficacy of each anti-D is being evaluated in several centers.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0041-1132
|
|
pubmed:author |
pubmed-author:AllanE KEK,
pubmed-author:Armstrong-FisherS SSS,
pubmed-author:CarterM CMC,
pubmed-author:DowningII,
pubmed-author:FraserR HRH,
pubmed-author:InglisG EGE,
pubmed-author:MackieAA,
pubmed-author:ProwseC VCV,
pubmed-author:TempletonJ GJG,
pubmed-author:ThorpeS JSJ,
pubmed-author:UrbaniakS JSJ
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
39
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1005-12
|
|
pubmed:dateRevised |
2007-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:10533828-Antibodies, Anti-Idiotypic,
pubmed-meshheading:10533828-Antibodies, Monoclonal,
pubmed-meshheading:10533828-Antigen-Antibody Reactions,
pubmed-meshheading:10533828-Drug Synergism,
pubmed-meshheading:10533828-Epitopes,
pubmed-meshheading:10533828-Evaluation Studies as Topic,
pubmed-meshheading:10533828-Female,
pubmed-meshheading:10533828-Humans,
pubmed-meshheading:10533828-Immunoglobulin G,
pubmed-meshheading:10533828-Isoantigens,
pubmed-meshheading:10533828-Pregnancy,
pubmed-meshheading:10533828-Rh Isoimmunization,
pubmed-meshheading:10533828-Rh-Hr Blood-Group System
|
|
pubmed:year |
1999
|
|
pubmed:articleTitle |
Evaluation of a panel of human monoclonal antibodies to D and exploration of the synergistic effects of blending IgG1 and IgG3 antibodies on their in vitro biologic function.
|
|
pubmed:affiliation |
Department of Medicine & Therapeutics, University of Aberdeen, Scotland. sylvia.armstrong@snbts.csa.scot.nhs.uk
|
|
pubmed:publicationType |
Journal Article,
Comparative Study
|
