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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1999-11-24
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pubmed:abstractText |
Angiotensin II (AngII) generation in response to vascular injury has long been assumed to influence neointimal proliferation contributing to restenosis. This concept has been supported by evidence that ACE inhibition and AT1 receptor blockade effectively limits restenosis in the rat. On the other hand, ACE inhibition has proven ineffective in clinical trails. The present study examines the response of the porcine coronary artery after angioplasty in vitro and compares the actions of an ACE inhibitor to AngII receptor antagonists.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin II,
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin Receptor Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin-Converting Enzyme...,
http://linkedlifedata.com/resource/pubmed/chemical/Antihypertensive Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Captopril,
http://linkedlifedata.com/resource/pubmed/chemical/EXP3174,
http://linkedlifedata.com/resource/pubmed/chemical/Imidazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Losartan,
http://linkedlifedata.com/resource/pubmed/chemical/PD 123319,
http://linkedlifedata.com/resource/pubmed/chemical/Pyridines,
http://linkedlifedata.com/resource/pubmed/chemical/Tetrazoles
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0008-6363
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
761-72
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:10533617-Analysis of Variance,
pubmed-meshheading:10533617-Angioplasty, Balloon, Coronary,
pubmed-meshheading:10533617-Angiotensin II,
pubmed-meshheading:10533617-Angiotensin Receptor Antagonists,
pubmed-meshheading:10533617-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:10533617-Animals,
pubmed-meshheading:10533617-Antihypertensive Agents,
pubmed-meshheading:10533617-Captopril,
pubmed-meshheading:10533617-Cell Division,
pubmed-meshheading:10533617-Coronary Disease,
pubmed-meshheading:10533617-Coronary Vessels,
pubmed-meshheading:10533617-Culture Techniques,
pubmed-meshheading:10533617-Imidazoles,
pubmed-meshheading:10533617-Losartan,
pubmed-meshheading:10533617-Muscle, Smooth, Vascular,
pubmed-meshheading:10533617-Pyridines,
pubmed-meshheading:10533617-Recurrence,
pubmed-meshheading:10533617-Swine,
pubmed-meshheading:10533617-Tetrazoles
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pubmed:year |
1999
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pubmed:articleTitle |
Angiotensin II receptor antagonists prevent neointimal proliferation in a porcine coronary artery organ culture model.
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pubmed:affiliation |
Department of Physiology, University of Manitoba, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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