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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1980-9-28
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pubmed:abstractText |
In the perfusion model under urethane anesthesia Wistar rats were two times injected pentagastrin subcutaneously in a distance of 150 minutes in dose rates of 50, 100, 150, 200, 250 and 300 microgram/kg b. w. The results may be summarized as follows: 1. The dose of 200 microgram/kg b. w. of pentagastrin produced the maximal answer. Higher doses showed a diminished acid secretion. 2. The diminished effect of higher doses of gastrin may be caused by a hypothetical inhibitor which may be more effective after truncal vagotomy. 3. The repeated injection of pentagastrin did not show a significant difference of the answer. The second injection was given after the acid secretion has returned to the basal level. No tachyphylaxy was seen under these conditions.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0323-5580
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
343-9
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:1053193-Animals,
pubmed-meshheading:1053193-Dose-Response Relationship, Drug,
pubmed-meshheading:1053193-Gastric Juice,
pubmed-meshheading:1053193-Injections, Subcutaneous,
pubmed-meshheading:1053193-Male,
pubmed-meshheading:1053193-Pentagastrin,
pubmed-meshheading:1053193-Perfusion,
pubmed-meshheading:1053193-Rats,
pubmed-meshheading:1053193-Stomach,
pubmed-meshheading:1053193-Tachyphylaxis,
pubmed-meshheading:1053193-Time Factors,
pubmed-meshheading:1053193-Vagus Nerve
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pubmed:year |
1975
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pubmed:articleTitle |
[Dose-response relationship of repeated injections of pentagastrin on the vagally innervated rat stomach in perfusion experiments].
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pubmed:publicationType |
Journal Article,
English Abstract
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