Source:http://linkedlifedata.com/resource/pubmed/id/10530941
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1999-11-18
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pubmed:abstractText |
The synthesis of a new family of antiviral compounds, 2-methoxy-, and 2-methylthio-6-[(2'-alkylamino)ethyl]-4(3H)-pyrimidinones, has been accomplished. The activity of these agents against positive strand (rubella virus and sindbis virus) and negative strand (vesicular stomatitis virus) RNA viruses is reported. Some of these compounds are efficient and selective inhibitors of rubella virus.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0968-0896
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1925-31
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:10530941-Animals,
pubmed-meshheading:10530941-Antiviral Agents,
pubmed-meshheading:10530941-Cell Survival,
pubmed-meshheading:10530941-Cercopithecus aethiops,
pubmed-meshheading:10530941-Microbial Sensitivity Tests,
pubmed-meshheading:10530941-Molecular Structure,
pubmed-meshheading:10530941-Pyrimidinones,
pubmed-meshheading:10530941-Rubella virus,
pubmed-meshheading:10530941-Spectrum Analysis,
pubmed-meshheading:10530941-Vero Cells,
pubmed-meshheading:10530941-Viral Plaque Assay
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pubmed:year |
1999
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pubmed:articleTitle |
Synthesis and biological evaluation of 2-methoxy- and 2-methylthio-6-[2'-alkylamino)ethyl]-4(3H)-pyrimidinones with anti-rubella virus activity.
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pubmed:affiliation |
Dipartimento Farmaco Chimico Tecnologico, Banchi di Sotto 55, Universitá degli Studi, Siena, Italy. botta@unisi.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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