Source:http://linkedlifedata.com/resource/pubmed/id/10530239
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1999-11-3
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pubmed:abstractText |
The cytotoxicity of three root-end filling materials (amalgam, IRM, and Super-EBA) was evaluated in cultures of human periodontal ligament cells and human osteoblast-like cells. Ten-millimeter-long plastic test tubes were filled with 3 mm of freshly mixed root-end filling materials at one end (1.5 mm diameter). The opposite end was sealed and attached by heat to a 35-mm cell culture dish. Human periodontal ligament cells and human osteoblast-like cells were seeded in the dishes. The size of cell-free zones around the root-end filling materials and the total cell number per dish were calculated after 3 and 7 days. Empty test tubes used as controls did not influence the growth and distribution of the cultured cells. Cell density increased in all groups in the test period. Amalgam had a larger cell-free zone, compared with IRM and Super-EBA and showed a reduction in total cell number per dish for both tested cell types. IRM and Super-EBA also had a cell-free inhibition zone for both cell types, but no significant reduction in total cell number per dish. This study showed that amalgam had a higher cell toxicity to human periodontal ligament cells and human osteoblast-like cells than IRM and Super-EBA.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
D
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Dental Amalgam,
http://linkedlifedata.com/resource/pubmed/chemical/Dentin-Bonding Agents,
http://linkedlifedata.com/resource/pubmed/chemical/IRM cement,
http://linkedlifedata.com/resource/pubmed/chemical/Methylmethacrylates,
http://linkedlifedata.com/resource/pubmed/chemical/Root Canal Filling Materials,
http://linkedlifedata.com/resource/pubmed/chemical/Super EBA,
http://linkedlifedata.com/resource/pubmed/chemical/Zinc Oxide-Eugenol Cement
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0099-2399
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
410-2
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:10530239-Analysis of Variance,
pubmed-meshheading:10530239-Cells, Cultured,
pubmed-meshheading:10530239-Dental Amalgam,
pubmed-meshheading:10530239-Dentin-Bonding Agents,
pubmed-meshheading:10530239-Humans,
pubmed-meshheading:10530239-Methylmethacrylates,
pubmed-meshheading:10530239-Osteoblasts,
pubmed-meshheading:10530239-Periodontal Ligament,
pubmed-meshheading:10530239-Retrograde Obturation,
pubmed-meshheading:10530239-Root Canal Filling Materials,
pubmed-meshheading:10530239-Zinc Oxide-Eugenol Cement
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pubmed:year |
1999
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pubmed:articleTitle |
Cytotoxic evaluation of root-end filling materials in cultures of human osteoblast-like cells and periodontal ligament cells.
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pubmed:affiliation |
Department of Restorative Dentistry and Endodontology, School of Dental Medicine, University of Connecticut Health Center, Farmington 06030-1715, USA.
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pubmed:publicationType |
Journal Article
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