Linked Life Data

10529749

Source:http://linkedlifedata.com/resource/pubmed/id/10529749

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2000-6-23
pubmed:abstractText
Amyotrophic lateral sclerosis (ALS) is a chronic degenerative disorder of unknown etiology affecting the motor system. Conventional and non-conventional neuroimaging techniques can provide essential help both to increase the confidence in ALS diagnosis and to assess the disease evolution. Signal abnormalities at the level of the motor cortex and the corticospinal tract on conventional T2-weighted magnetic resonance (MR) images are a potentially useful marker of ALS pathology. However, the prognostic value of these conventional MR abnormalities is still hampered by their low pathological specificity. Non-conventional MR techniques with a higher pathological specificity, such as MR spectroscopy, magnetization transfer imaging and diffusion-weighted imaging, seem to have some potential not only for ALS diagnosis, but also for monitoring disease evolution either naturally or when modified by experimental treatments.
pubmed:language
eng
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:author
pubmed:copyrightInfo
Copyright 1999 Lippincott Williams & Wilkins
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
629-37
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:articleTitle
Review neuroimaging in amyotrophic lateral sclerosis.
pubmed:affiliation
Department of Neurophysiopathology, Scientific Institute Ospedale San Raffaele, Via Olgettina 60, 20132, Milan, Italy. g.comi@hsr.it
pubmed:publicationType
Journal Article, Review