|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
10
|
|
pubmed:dateCreated |
1999-12-1
|
|
pubmed:abstractText |
Sulphatide and insulin are present in the secretory granules and at the surface of beta cells in islets of Langerhans. Insulin autoantibodies and T-cell reactivity against insulin exist during the development of Type I (insulin-dependent) diabetes during which active beta cells may be more vulnerable than passive. Our aims were to examine the presence of sulphatide in active and passive beta cells and to clarify whether sulphatide influences the direct autoimmunity against insulin.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0012-186X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
42
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1212-8
|
|
pubmed:dateRevised |
2011-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:10525662-Animals,
pubmed-meshheading:10525662-Cells, Cultured,
pubmed-meshheading:10525662-Cerebrosides,
pubmed-meshheading:10525662-Clone Cells,
pubmed-meshheading:10525662-Cytoplasmic Granules,
pubmed-meshheading:10525662-Diabetes Mellitus, Type 1,
pubmed-meshheading:10525662-Insulin,
pubmed-meshheading:10525662-Islets of Langerhans,
pubmed-meshheading:10525662-Light,
pubmed-meshheading:10525662-Lymphocyte Activation,
pubmed-meshheading:10525662-Male,
pubmed-meshheading:10525662-Microscopy, Electron,
pubmed-meshheading:10525662-Rats,
pubmed-meshheading:10525662-Rats, Inbred Lew,
pubmed-meshheading:10525662-Scattering, Radiation,
pubmed-meshheading:10525662-T-Lymphocytes
|
|
pubmed:year |
1999
|
|
pubmed:articleTitle |
Inhibition of insulin-specific autoreactive T-cells by sulphatide which is variably expressed in beta cells.
|
|
pubmed:affiliation |
Bartholin Instituttet, Kommunehospitalet, Copenhagen, Denmark.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
