|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0011889,
umls-concept:C0014442,
umls-concept:C0018787,
umls-concept:C0030685,
umls-concept:C0035124,
umls-concept:C0057676,
umls-concept:C0205265,
umls-concept:C0205409,
umls-concept:C0391871,
umls-concept:C0680255,
umls-concept:C1283071,
umls-concept:C1383501,
umls-concept:C1555582,
umls-concept:C1883709,
umls-concept:C1963578
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|
pubmed:issue |
4
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|
pubmed:dateCreated |
1999-11-16
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|
pubmed:abstractText |
Reperfusion injury after cardioplegia may not be sufficiently addressed by conventional cardioplegic techniques in open heart surgery. 2,3-butanedione monoxime (BDM) has the potential to reduce myocardial reperfusion injury by uncoupling myocyte contraction from the intracellular calcium concentration, thus reducing reperfusion contracture. The aim of this study was to investigate the effects of different application periods of BDM during initial reperfusion on myocardial tissue injury after cardioplegia.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
0171-6425
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
47
|
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
244-50
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|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:10522795-Animals,
pubmed-meshheading:10522795-Biological Markers,
pubmed-meshheading:10522795-Creatine Kinase,
pubmed-meshheading:10522795-Diacetyl,
pubmed-meshheading:10522795-Guinea Pigs,
pubmed-meshheading:10522795-L-Lactate Dehydrogenase,
pubmed-meshheading:10522795-Myocardial Reperfusion,
pubmed-meshheading:10522795-Myocardial Reperfusion Injury,
pubmed-meshheading:10522795-Myocardium,
pubmed-meshheading:10522795-Organ Preservation Solutions,
pubmed-meshheading:10522795-Time Factors,
pubmed-meshheading:10522795-Troponin I
|
|
pubmed:year |
1999
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|
pubmed:articleTitle |
Time-dependent efficacy of initial reperfusion with 2,3 butanedione monoxime (BDM) on release of cytosolic enzymes and ultrastructural damage in isolated hearts.
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pubmed:affiliation |
Institute for Surgical Research, Klinikum Grosshadern, University of Munich, Germany.
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pubmed:publicationType |
Journal Article,
In Vitro
|
