Source:http://linkedlifedata.com/resource/pubmed/id/10522181
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1999-10-20
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pubmed:abstractText |
The objective of this study was to evaluate the effect of bone morphogenetic protein (BMP) on the bond strength of titanium (Ti) implants at the bone-implant interface. Thirty-six Brånemark screw implants (3.75 mm diameter by 15 mm long) were implanted for 3 and 12 weeks. At 3 weeks after implantation, the mean reverse torque value for implants stimulated with BMP delivered using an atelopeptide type-I collagen carrier (74.2 +/- 5.2 N cm) was observed to be statistically greater (P < 0.000016) than the mean reverse torque value for control Ti implants (32.8 +/- 1.1 N cm). Similarly, at 12 weeks after implantation, the mean reverse torque value for implants stimulated with BMP (89.2 +/- 2.7 N cm) was statistically greater (P < 0.0042) than the mean reverse torque value for control Ti implants (75.8 +/- 2.4 N cm). In addition, histomorphometric evaluations indicated more bone contact with the BMP stimulated implant surfaces compared to the controls after 3 weeks implantation. It was concluded from this study that the use of BMP-atelopeptide type-I collagen mixture is an effective means of obtaining greater bond strength at the bone implant interface within a shorter time period than Ti implants without BMP.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
D
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Bone Morphogenetic Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Collagen,
http://linkedlifedata.com/resource/pubmed/chemical/Dental Implants,
http://linkedlifedata.com/resource/pubmed/chemical/Drug Carriers,
http://linkedlifedata.com/resource/pubmed/chemical/Titanium,
http://linkedlifedata.com/resource/pubmed/chemical/atelocollagen
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0905-7161
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
212-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10522181-Animals,
pubmed-meshheading:10522181-Bone Morphogenetic Proteins,
pubmed-meshheading:10522181-Collagen,
pubmed-meshheading:10522181-Dental Implantation, Endosseous,
pubmed-meshheading:10522181-Dental Implants,
pubmed-meshheading:10522181-Dogs,
pubmed-meshheading:10522181-Drug Carriers,
pubmed-meshheading:10522181-Implants, Experimental,
pubmed-meshheading:10522181-Male,
pubmed-meshheading:10522181-Osseointegration,
pubmed-meshheading:10522181-Titanium,
pubmed-meshheading:10522181-Torque
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pubmed:year |
1999
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pubmed:articleTitle |
BMP stimulation of bone response adjacent to titanium implants in vivo.
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pubmed:affiliation |
Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Kyoto University, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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