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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
1999-11-24
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pubmed:abstractText |
This study was undertaken to investigate the prevalence of coeliac disease in children and adolescents with Turner syndrome. Eighty-seven children and adolescents with Turner syndrome were screened for IgA-antiendomysium antibodies (EMA) and IgA-antigliadin antibodies (AGA), 5% (4/87) being found to be EMA-positive, and 15% (13/87) to have AGA levels above normal. Of the 10 patients who were either AGA- or EMA-positive and further investigated with intestinal biopsy, four manifested villous atrophy (i.e. all three of the EMA-positive patients, but only one of the seven AGA-positive patients). The results suggest EMA-positivity to be a good immunological marker for use in screening for coeliac disease, and such screening to be justified in patients with Turner syndrome.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0803-5253
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pubmed:author |
pubmed-author:Albertsson-WiklandKK,
pubmed-author:AltAA,
pubmed-author:AronssonSS,
pubmed-author:BOCKFF,
pubmed-author:BredbergAA,
pubmed-author:CarlssonAA,
pubmed-author:GustafssonJJ,
pubmed-author:HägerAA,
pubmed-author:HagenäsLL,
pubmed-author:IvarssonS ASA,
pubmed-author:KriströmBB,
pubmed-author:MarcusCC,
pubmed-author:MoëllCC,
pubmed-author:NilssonK OKO,
pubmed-author:TuvemoTT,
pubmed-author:WestphalOO
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pubmed:issnType |
Print
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pubmed:volume |
88
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
933-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10519331-Adolescent,
pubmed-meshheading:10519331-Antibodies, Anti-Idiotypic,
pubmed-meshheading:10519331-Case-Control Studies,
pubmed-meshheading:10519331-Celiac Disease,
pubmed-meshheading:10519331-Child,
pubmed-meshheading:10519331-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:10519331-Female,
pubmed-meshheading:10519331-Gliadin,
pubmed-meshheading:10519331-Humans,
pubmed-meshheading:10519331-Immunoglobulin A,
pubmed-meshheading:10519331-Prevalence,
pubmed-meshheading:10519331-Sweden,
pubmed-meshheading:10519331-Turner Syndrome
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pubmed:year |
1999
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pubmed:articleTitle |
Prevalence of coeliac disease in Turner syndrome.
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pubmed:affiliation |
Department of Paediatrics, University of Lund, University Hospital, Malmö, Sweden.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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