Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1999-11-16
pubmed:abstractText
We studied the effect of oral contraceptives and smoking on the lipid profile of 251 women and 72 men, 20-29-year-old. In women, taking estroprogestatives, cholesterol, triglycerides, apoproteins AI and B were higher than in controls; HDL-cholesterol was not modified. Lipoprotein analyses in polyacrylamide gradient gel exhibited an increase of the HDL3 fraction at the expense of the HDL2 fraction, with a reduced LDL size. Smoking in addition to estroprogestative absorption accentuated these modifications and led to a decreased HDL-cholesterol (HDL2 fraction essentially), with an increased LDL-cholesterol. In men, smoking resulted in higher levels of total cholesterol, apoprotein B and LDL-cholesterol, without any significant change in LDL size, higher levels of triglycerides and lower level of the HDL2 fraction without any change in HDL-cholesterol. In women, smoking led only to an increase in triglycerides. In summary, analysis of the distribution of HDL subclasses and of LDL size showed an evolution towards a supposed more atherogenic lipid profile in women taking oral contraceptives associated or not with smoking, and in male smokers.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Apolipoprotein A-I, http://linkedlifedata.com/resource/pubmed/chemical/Apolipoproteins B, http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, HDL, http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, LDL, http://linkedlifedata.com/resource/pubmed/chemical/Contraceptive Agents, Female, http://linkedlifedata.com/resource/pubmed/chemical/Contraceptives, Oral, Hormonal, http://linkedlifedata.com/resource/pubmed/chemical/Desogestrel, http://linkedlifedata.com/resource/pubmed/chemical/Estradiol Congeners, http://linkedlifedata.com/resource/pubmed/chemical/Ethinyl Estradiol, http://linkedlifedata.com/resource/pubmed/chemical/Levonorgestrel, http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, http://linkedlifedata.com/resource/pubmed/chemical/Progesterone Congeners, http://linkedlifedata.com/resource/pubmed/chemical/Triglycerides
pubmed:status
MEDLINE
pubmed:issn
0003-3898
pubmed:author
pubmed:issnType
Print
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
573-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:10518059-Adult, pubmed-meshheading:10518059-Apolipoprotein A-I, pubmed-meshheading:10518059-Apolipoproteins B, pubmed-meshheading:10518059-Arteriosclerosis, pubmed-meshheading:10518059-Cholesterol, pubmed-meshheading:10518059-Cholesterol, HDL, pubmed-meshheading:10518059-Cholesterol, LDL, pubmed-meshheading:10518059-Contraceptive Agents, Female, pubmed-meshheading:10518059-Contraceptives, Oral, Hormonal, pubmed-meshheading:10518059-Desogestrel, pubmed-meshheading:10518059-Electrophoresis, Polyacrylamide Gel, pubmed-meshheading:10518059-Estradiol Congeners, pubmed-meshheading:10518059-Ethinyl Estradiol, pubmed-meshheading:10518059-Female, pubmed-meshheading:10518059-Humans, pubmed-meshheading:10518059-Levonorgestrel, pubmed-meshheading:10518059-Lipoproteins, pubmed-meshheading:10518059-Male, pubmed-meshheading:10518059-Progesterone Congeners, pubmed-meshheading:10518059-Smoking, pubmed-meshheading:10518059-Triglycerides
pubmed:articleTitle
[Effects of oral contraceptive preparations and smoking on lipoprotein repartition].
pubmed:affiliation
Laboratoire de biochimie A, CHU, BP 217, 38043 Grenoble Cedex 09.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't