Source:http://linkedlifedata.com/resource/pubmed/id/10515818
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
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| pubmed:dateCreated |
1999-12-9
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| pubmed:abstractText |
Antimicrobial susceptibility, pneumococcal surface protein A (PspA) serotyping, and pulsed-field gel electrophoresis (PFGE) were used to evaluate clonal relatedness among 66 invasive isolates of Streptococcus pneumoniae serotype 6B collected during 1982-1996 from patients in Alaska. Thirty-seven (56%) of the isolates had penicillin minimal inhibitory concentration values >/=0.125 microgram/mL and were resistant to at least 1 other antibiotic. Fourteen PspA serotypes were observed; PspA 16 was the most common (35%). Forty-five (68%) of the 66 isolates shared common and highly related PFGE patterns using 3 enzymes. Twenty-six (58%) of the isolates with common PFGE patterns were from Native Alaskan children </=2 years of age residing in 1 region of Alaska. Alaskan serotype 6B had distinct PFGE patterns, compared with the South African 6B-8 and Spanish 6B-2 multidrug-resistant clones, suggesting that the Alaskan 6B isolates were distinct from these other pneumococcal 6B clones but were genetically related to each other [corrected].
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| pubmed:commentsCorrections | |
| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
AIM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Nov
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| pubmed:issn |
0022-1899
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
180
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
1577-83
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:10515818-Adolescent,
pubmed-meshheading:10515818-Adult,
pubmed-meshheading:10515818-Aged,
pubmed-meshheading:10515818-Aged, 80 and over,
pubmed-meshheading:10515818-Alaska,
pubmed-meshheading:10515818-Anti-Bacterial Agents,
pubmed-meshheading:10515818-Bacterial Proteins,
pubmed-meshheading:10515818-Bacterial Typing Techniques,
pubmed-meshheading:10515818-Child,
pubmed-meshheading:10515818-Child, Preschool,
pubmed-meshheading:10515818-Drug Resistance, Microbial,
pubmed-meshheading:10515818-Drug Resistance, Multiple,
pubmed-meshheading:10515818-Electrophoresis, Gel, Pulsed-Field,
pubmed-meshheading:10515818-Female,
pubmed-meshheading:10515818-Humans,
pubmed-meshheading:10515818-Infant,
pubmed-meshheading:10515818-Male,
pubmed-meshheading:10515818-Microbial Sensitivity Tests,
pubmed-meshheading:10515818-Middle Aged,
pubmed-meshheading:10515818-Pneumococcal Infections,
pubmed-meshheading:10515818-Serotyping,
pubmed-meshheading:10515818-Streptococcus pneumoniae
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| pubmed:year |
1999
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| pubmed:articleTitle |
Characterization of a multidrug-resistant clone of invasive Streptococcus pneumoniae serotype 6B in Alaska by using pulsed-field gel electrophoresis and PspA serotyping.
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| pubmed:affiliation |
Molecular Diagnostics Lab, Arctic Investigations Program, Anchorage, AK 990508, USA. kmr2@cdc.gov
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| pubmed:publicationType |
Journal Article
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