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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
18
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pubmed:dateCreated |
1999-11-4
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pubmed:abstractText |
Analogs of compound 1 with a variety of azacycles and heteroaryl groups were synthesized. These analogs exhibited Ki values ranging from 0.15 to > 10,000 nM when tested in vitro for cholinergic channel receptor binding activity (displacement of [3H](-) cytisine from whole rat brain synaptic membranes).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0960-894X
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pubmed:author |
pubmed-author:AbreoM AMA,
pubmed-author:ArnericS PSP,
pubmed-author:CampbellJ EJE,
pubmed-author:DaanenJ FJF,
pubmed-author:GarveyD SDS,
pubmed-author:GunnD EDE,
pubmed-author:HettingerA MAM,
pubmed-author:LeboldS ASA,
pubmed-author:LeeE LEL,
pubmed-author:LinN HNH,
pubmed-author:SullivanJ PJP,
pubmed-author:WasicakJ TJT,
pubmed-author:WilliamsMM
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pubmed:issnType |
Print
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pubmed:day |
20
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2747-52
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
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pubmed:year |
1999
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pubmed:articleTitle |
Structure-activity studies on a novel series of cholinergic channel activators based on a heteroaryl ether framework.
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pubmed:affiliation |
Abbott Laboratories, Abbott Park, IL 60064-3500, USA.
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pubmed:publicationType |
Journal Article
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