Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1999-11-16
pubmed:abstractText
Biological considerations support the use of primary chemotherapy in operable breast cancer; and despite wide variations of used regimens, clinical studies consistently show a significant tumor response allowing breast conservation in many patients otherwise candidates for mastectomy. We investigated the efficacy and the acceptance of a combination chemotherapy with vinorelbine, 5-fluorouracil and high-dose folinic acid in operable breast cancer with favorable prognostic factors and tested the relationship of hormone receptor status, Ki67,p53, c-erbB2 and bcl-2 with treatment response.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0923-7534
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
993-6
pubmed:dateRevised
2006-4-24
pubmed:meshHeading
pubmed-meshheading:10509165-Adult, pubmed-meshheading:10509165-Aged, pubmed-meshheading:10509165-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:10509165-Biopsy, pubmed-meshheading:10509165-Breast Neoplasms, pubmed-meshheading:10509165-Disease-Free Survival, pubmed-meshheading:10509165-Dose-Response Relationship, Drug, pubmed-meshheading:10509165-Drug Administration Schedule, pubmed-meshheading:10509165-Female, pubmed-meshheading:10509165-Fluorouracil, pubmed-meshheading:10509165-Humans, pubmed-meshheading:10509165-Leucovorin, pubmed-meshheading:10509165-Middle Aged, pubmed-meshheading:10509165-Neoplasm Staging, pubmed-meshheading:10509165-Pilot Projects, pubmed-meshheading:10509165-Prognosis, pubmed-meshheading:10509165-Receptors, Estrogen, pubmed-meshheading:10509165-Receptors, Progesterone, pubmed-meshheading:10509165-Survival Rate, pubmed-meshheading:10509165-Treatment Outcome, pubmed-meshheading:10509165-Vinblastine
pubmed:year
1999
pubmed:articleTitle
Primary chemotherapy in operable breast cancer with favorable prognostic factors: a pilot study evaluating the efficacy of a regimen with a low subjective toxic burden containing vinorelbine, 5-fluorouracil and folinic acid (FLN).
pubmed:affiliation
Division of Medical Oncology, European Institute of Oncology, Milan, Italy. fnole@ieo.it
pubmed:publicationType
Journal Article, Clinical Trial