Source:http://linkedlifedata.com/resource/pubmed/id/10506724
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1999-10-18
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pubmed:abstractText |
The diagnosis of leptomeningeal dissemination of malignant glioma (meningeal gliomatosis) is associated with poor survival. Intrathecal (IT) chemotherapeutic agents used to achieve tumor control and improve survival include methotrexate, cytosine arabinoside (ara-C), thiotriethylenephosphoramide (thio-TEPA), neocarzinostatin, and 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitros ourea hydrochloride (ACNU). Little information exists about survival following administration of IT chemotherapy. The authors report survival data from a series of patients with supratentorial anaplastic astrocytoma (AA) or glioblastoma multiforme (GBM) treated for ependymal or leptomeningeal gliomatosis with IT thio-TEPA.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 1999 American Cancer Society.
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
86
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1347-53
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10506724-Adult,
pubmed-meshheading:10506724-Antineoplastic Agents, Alkylating,
pubmed-meshheading:10506724-Arachnoid,
pubmed-meshheading:10506724-Brain Neoplasms,
pubmed-meshheading:10506724-Ependyma,
pubmed-meshheading:10506724-Female,
pubmed-meshheading:10506724-Glioma,
pubmed-meshheading:10506724-Humans,
pubmed-meshheading:10506724-Injections, Spinal,
pubmed-meshheading:10506724-Magnetic Resonance Imaging,
pubmed-meshheading:10506724-Male,
pubmed-meshheading:10506724-Middle Aged,
pubmed-meshheading:10506724-Pia Mater,
pubmed-meshheading:10506724-Retrospective Studies,
pubmed-meshheading:10506724-Thiotepa,
pubmed-meshheading:10506724-Treatment Outcome
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pubmed:year |
1999
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pubmed:articleTitle |
Survival of patients with high grade glioma treated with intrathecal thiotriethylenephosphoramide for ependymal or leptomeningeal gliomatosis.
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pubmed:affiliation |
Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.
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