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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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|
pubmed:dateCreated |
2000-1-4
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pubmed:abstractText |
Several agents have been evaluated for their effect as biochemical modulators of fluorouracil (5-FU) in the treatment of metastatic colorectal carcinoma. In this study, we used folinic acid (FA), N-phosphonacetyl-L-aspartic acid (PALA), and recombinant interferon alfa-2a (IFNalpha-2a) in a sequential order to assess the efficacy of this approach in patients with metastatic colorectal carcinoma.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0732-183X
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3276-82
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:10506630-Adult,
pubmed-meshheading:10506630-Aged,
pubmed-meshheading:10506630-Aged, 80 and over,
pubmed-meshheading:10506630-Antimetabolites, Antineoplastic,
pubmed-meshheading:10506630-Antineoplastic Agents,
pubmed-meshheading:10506630-Aspartic Acid,
pubmed-meshheading:10506630-Colorectal Neoplasms,
pubmed-meshheading:10506630-Combined Modality Therapy,
pubmed-meshheading:10506630-Drug Administration Schedule,
pubmed-meshheading:10506630-Drug Interactions,
pubmed-meshheading:10506630-Female,
pubmed-meshheading:10506630-Fluorouracil,
pubmed-meshheading:10506630-Humans,
pubmed-meshheading:10506630-Immunologic Factors,
pubmed-meshheading:10506630-Infusions, Intravenous,
pubmed-meshheading:10506630-Injections, Intravenous,
pubmed-meshheading:10506630-Injections, Subcutaneous,
pubmed-meshheading:10506630-Interferon-alpha,
pubmed-meshheading:10506630-Leucovorin,
pubmed-meshheading:10506630-Male,
pubmed-meshheading:10506630-Middle Aged,
pubmed-meshheading:10506630-Phosphonoacetic Acid,
pubmed-meshheading:10506630-Survival Analysis,
pubmed-meshheading:10506630-Treatment Outcome
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pubmed:year |
1999
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pubmed:articleTitle |
Sequential biochemical modulation of fluorouracil with folinic acid, N-phosphonacetyl-L-aspartic acid, and interferon alfa-2a in advanced colorectal cancer.
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pubmed:affiliation |
Division of Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.
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