Source:http://linkedlifedata.com/resource/pubmed/id/10503098
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1999-10-26
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| pubmed:abstractText |
1. The 5-year actuarial graft, patient and functional graft survival rates were analyzed in 743 consecutive primary cadaveric kidney transplants from The Toronto Hospital between January 1985-December 1997. 2. Recipient age > or = 55 years, male recipient sex, recipient diabetes mellitus, CIT > 36 hours and delayed graft function were found to significantly decrease patient survival. 3. Recipient age > or = 55 years, sensitization to HLA antigens (peak PRA > 50%), donor/recipient HLA antigen mismatches, CIT > 36 hours, delayed graft, function and 6-month SCr > 200 mumol/L were found to significantly decrease graft survival. 4. Acute rejection episodes had no significant impact on overall 5-year patient or graft survival. 5. The observation that serum creatinine > 200 mumol/L had a major adverse influence on long-term outcome reflects the importance of functional renal mass on graft survival.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:issn |
0890-9016
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
195-203
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:10503098-Adult,
pubmed-meshheading:10503098-Age Factors,
pubmed-meshheading:10503098-Cadaver,
pubmed-meshheading:10503098-Diabetic Nephropathies,
pubmed-meshheading:10503098-Female,
pubmed-meshheading:10503098-Graft Rejection,
pubmed-meshheading:10503098-Graft Survival,
pubmed-meshheading:10503098-Histocompatibility Testing,
pubmed-meshheading:10503098-Hospitals, University,
pubmed-meshheading:10503098-Humans,
pubmed-meshheading:10503098-Kidney Diseases,
pubmed-meshheading:10503098-Kidney Transplantation,
pubmed-meshheading:10503098-Male,
pubmed-meshheading:10503098-Middle Aged,
pubmed-meshheading:10503098-Ontario,
pubmed-meshheading:10503098-Retrospective Studies,
pubmed-meshheading:10503098-Survival Rate,
pubmed-meshheading:10503098-Tissue Donors
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| pubmed:year |
1998
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| pubmed:articleTitle |
Factors influencing long-term primary cadaveric kidney transplantation--importance of functional renal mass versus avoidance of acute rejections--the Toronto Hospital experience 1985-1997.
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| pubmed:affiliation |
Multi Organ Transplant Unit, Toronto Hospital, University of Toronto, Ontario, Canada.
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| pubmed:publicationType |
Journal Article
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