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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1999-11-12
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pubmed:abstractText |
In order to assess the effect of the tyrosine kinase inhibitor CGP57148B on lineage-committed and primitive chronic myelogenous leukemia (CML) progenitor cells, peripheral blood progenitor cells (PBPC) mobilized in chronic phase CML were exposed to this compound in vitro.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0344-5704
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
433-8
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:10501919-Antineoplastic Agents,
pubmed-meshheading:10501919-Coculture Techniques,
pubmed-meshheading:10501919-Colony-Forming Units Assay,
pubmed-meshheading:10501919-Drug Screening Assays, Antitumor,
pubmed-meshheading:10501919-Enzyme Inhibitors,
pubmed-meshheading:10501919-Fusion Proteins, bcr-abl,
pubmed-meshheading:10501919-Hematopoietic Stem Cells,
pubmed-meshheading:10501919-Humans,
pubmed-meshheading:10501919-Leukemia, Myelogenous, Chronic, BCR-ABL Positive,
pubmed-meshheading:10501919-Piperazines,
pubmed-meshheading:10501919-Protein-Tyrosine Kinases,
pubmed-meshheading:10501919-Pyrimidines,
pubmed-meshheading:10501919-Stromal Cells,
pubmed-meshheading:10501919-Tumor Cells, Cultured
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pubmed:year |
1999
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pubmed:articleTitle |
Favorable therapeutic index of a p210(BCR-ABL)-specific tyrosine kinase inhibitor; activity on lineage-committed and primitive chronic myelogenous leukemia progenitors.
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pubmed:affiliation |
German Cancer Research Center (DKFZ), Diagnostics and Experimental Therapy, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.
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pubmed:publicationType |
Journal Article
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