Source:http://linkedlifedata.com/resource/pubmed/id/10500292
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
1999-11-5
|
| pubmed:abstractText |
Dysfunctional immunoglobulins (Igs) that are prone to aggregation are unavoidably generated by the diverse repertoire of B cells. Here, Fred Stevens and Yair Argon analyse the patterns of mutations that lead to pathological Igs, account for non-random mutations in human Ig sequences and suggest the exertion of selective forces, which contribute to determining and limiting the Ig repertoire.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0167-5699
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
20
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
451-7
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:10500292-B-Lymphocytes,
pubmed-meshheading:10500292-Humans,
pubmed-meshheading:10500292-Immunoglobulin Light Chains,
pubmed-meshheading:10500292-Models, Molecular,
pubmed-meshheading:10500292-Mutation,
pubmed-meshheading:10500292-Paraproteinemias,
pubmed-meshheading:10500292-Protein Folding
|
| pubmed:year |
1999
|
| pubmed:articleTitle |
Pathogenic light chains and the B-cell repertoire.
|
| pubmed:affiliation |
Biosciences Division, Argonne National Laboratory, Argonne, IL, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Review,
Research Support, Non-U.S. Gov't
|