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rdf:type |
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lifeskim:mentions |
umls-concept:C0006100,
umls-concept:C0028128,
umls-concept:C0030705,
umls-concept:C0042401,
umls-concept:C0127400,
umls-concept:C0205224,
umls-concept:C0221099,
umls-concept:C0441712,
umls-concept:C0470187,
umls-concept:C0857121,
umls-concept:C1704259,
umls-concept:C1705987
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|
pubmed:issue |
13
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|
pubmed:dateCreated |
1999-10-20
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|
pubmed:abstractText |
In essential hypertension, endothelium-dependent vasodilation is impaired because of reduced nitric oxide (NO) availability, which is mainly caused by oxidative stress. The present study was designed to identify the mechanism(s) responsible for NO-independent vasodilation to bradykinin in patients with essential hypertension.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
28
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pubmed:volume |
100
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1400-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:10500040-Adaptation, Physiological,
pubmed-meshheading:10500040-Adult,
pubmed-meshheading:10500040-Antioxidants,
pubmed-meshheading:10500040-Ascorbic Acid,
pubmed-meshheading:10500040-Biological Availability,
pubmed-meshheading:10500040-Bradykinin,
pubmed-meshheading:10500040-Drug Combinations,
pubmed-meshheading:10500040-Enzyme Inhibitors,
pubmed-meshheading:10500040-Female,
pubmed-meshheading:10500040-Humans,
pubmed-meshheading:10500040-Hypertension,
pubmed-meshheading:10500040-Male,
pubmed-meshheading:10500040-Middle Aged,
pubmed-meshheading:10500040-Nitric Oxide,
pubmed-meshheading:10500040-Nitroprusside,
pubmed-meshheading:10500040-Ouabain,
pubmed-meshheading:10500040-Reference Values,
pubmed-meshheading:10500040-Vasodilation,
pubmed-meshheading:10500040-Vasodilator Agents,
pubmed-meshheading:10500040-omega-N-Methylarginine
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pubmed:year |
1999
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pubmed:articleTitle |
Vasodilation to bradykinin is mediated by an ouabain-sensitive pathway as a compensatory mechanism for impaired nitric oxide availability in essential hypertensive patients.
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pubmed:affiliation |
Department of Internal Medicine, University of Pisa, Italy. s.taddei@int.med.unipi.it
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pubmed:publicationType |
Journal Article
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