Linked Life Data

10498274

Source:http://linkedlifedata.com/resource/pubmed/id/10498274

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1999-11-4
pubmed:abstractText
The formation of discrete functional areas is a key event in the development of the cerebral cortex. The expression patterns of several molecules associated with axon guidance reveal specification of regional identity during fetal development within the cortex, with different area-specific features acquired at very early to later stages of corticogenesis. Cell culture experiments suggest that complex mechanisms regulate the differentiation of region-appropriate phenotypes. In all instances that we have examined thus far, however, the final phenotype adopted by cortical neurons is governed by the capacity of the cell to respond to regionalizing signals; this is reflected in the heterogeneity of receptor expression by progenitors, and the temporal and spatial distribution of such signals within the forebrain.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1047-3211
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
562-8
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Complex signaling responsible for molecular regionalization of the cerebral cortex.
pubmed:affiliation
Department of Neurobiology, University of Pittsburgh School of Medicine, PA 15261, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't