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10498206
Source:
http://linkedlifedata.com/resource/pubmed/id/10498206
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Statements in which the resource exists as a subject.
Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0038734
,
umls-concept:C0220781
,
umls-concept:C0243077
,
umls-concept:C0268563
,
umls-concept:C0597572
,
umls-concept:C1825576
,
umls-concept:C1883254
pubmed:issue
17
pubmed:dateCreated
1999-10-28
pubmed:abstractText
Potent thioester and thiol inhibitors of IMP-1 metallo-beta-lactamase have been synthesized employing a solid-phase Mitsunobu reaction as the key step.
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Bacterial Proteins
,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors
,
http://linkedlifedata.com/resource/pubmed/chemical/Esters
,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfhydryl Compounds
,
http://linkedlifedata.com/resource/pubmed/chemical/beta-Lactamases
,
http://linkedlifedata.com/resource/pubmed/chemical/cphA protein, Aeromonas hydrophila
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0960-894X
pubmed:author
pubmed-author:BalkovecJ MJM
,
pubmed-author:Epstein-ToneyJ HJH
,
pubmed-author:GreenleeM LML
,
pubmed-author:HammondG GGG
,
pubmed-author:HammondM LML
,
pubmed-author:LaubJ BJB
,
pubmed-author:PomplianoD LDL
pubmed:issnType
Print
pubmed:day
6
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2549-54
pubmed:dateRevised
2004-2-11
pubmed:meshHeading
pubmed-meshheading:10498206-Bacterial Proteins
,
pubmed-meshheading:10498206-Enzyme Inhibitors
,
pubmed-meshheading:10498206-Esters
,
pubmed-meshheading:10498206-Structure-Activity Relationship
,
pubmed-meshheading:10498206-Sulfhydryl Compounds
,
pubmed-meshheading:10498206-beta-Lactamases
pubmed:year
1999
pubmed:articleTitle
Synthesis and SAR of thioester and thiol inhibitors of IMP-1 metallo-beta-lactamase.
pubmed:affiliation
Department of Medicinal Chemistry, Merck Research Laboratorie, Rahway, NJ 07065, USA.
pubmed:publicationType
Journal Article