Source:http://linkedlifedata.com/resource/pubmed/id/10498136
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
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| pubmed:dateCreated |
1999-10-6
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| pubmed:abstractText |
This study assesses the vasovagal collapse pattern changes, i.e, heart rate (HR) and arterial blood pressure (BP) with a 2-stage tilt-test protocol using glyceryl trinitrate (GTN) provocation. With use of the 45-minute 60 degrees head-up Westminster protocol, 102 consecutive patients were studied. Sublingual GTN 300 microg was given to those with a negative passive tilt. Heart rate and BP patterns were classified according to the Vasovagal International Study classification (VASIS) and then compared between those with a positive passive tilt and those with a positive tilt after having been given GTN. Twelve patients did not tolerate tilt testing, and 16 had a negative response despite taking GTN. Thirty-five patients (20 women and 15 men, mean age 45 +/- 21 years [mean +/- SD]) did not take GTN and 38 (26 women and 12 men, mean age 53 +/- 22 years) had positive passive test results. When comparing the VASIS classification between the 2 groups, results showed: type 1, mixed BP and HR decreased without severe bradycardia (31% [passive] vs 54% [with GTN], p = NS); type 2A, BP decreased before HR decreased (20% vs 22%, p = NS); type 2B, HR decreased before or coincident with BP (34% vs 8%, p = 0.003); type 3, BP decreased without HR decrease (9% vs 0%, p = NS); exception 1, chronotropic incompetence (0% vs 13%, p = 0.026); and exception 2, excessive HR increase (6% vs 3%, p = NS). Thus, GTN use increases frequency of positive results from 34% to 73%. Older people with chronotropic incompetence, who may benefit from pacing, were identified. In younger people there was an increase in those with cardioinhibition.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
AIM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Sep
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| pubmed:issn |
0002-9149
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:day |
15
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| pubmed:volume |
84
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
665-70
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:10498136-Administration, Sublingual,
pubmed-meshheading:10498136-Adolescent,
pubmed-meshheading:10498136-Adult,
pubmed-meshheading:10498136-Age Factors,
pubmed-meshheading:10498136-Aged,
pubmed-meshheading:10498136-Aged, 80 and over,
pubmed-meshheading:10498136-Blood Pressure,
pubmed-meshheading:10498136-Child,
pubmed-meshheading:10498136-Diagnosis, Differential,
pubmed-meshheading:10498136-Female,
pubmed-meshheading:10498136-Heart Rate,
pubmed-meshheading:10498136-Humans,
pubmed-meshheading:10498136-Male,
pubmed-meshheading:10498136-Middle Aged,
pubmed-meshheading:10498136-Nitroglycerin,
pubmed-meshheading:10498136-Sex Factors,
pubmed-meshheading:10498136-Syncope, Vasovagal,
pubmed-meshheading:10498136-Tilt-Table Test,
pubmed-meshheading:10498136-Vasodilator Agents
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| pubmed:year |
1999
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| pubmed:articleTitle |
Usefulness of tilt test-induced patterns of heart rate and blood pressure using a two-stage protocol with glyceryl trinitrate provocation in patients with syncope of unknown origin.
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| pubmed:affiliation |
St Mary's Hospital, Imperial College School of Medicine, University of London, United Kingdom. a.kurbaan@rbh.nthames.nhs.uk
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| pubmed:publicationType |
Journal Article
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