Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1999-10-26
pubmed:abstractText
We studied the relationship between different ethnic groups, obstructive sleep apnoea (OSA) and ischaemic heart disease. Four hundred and thirty-two inpatients from the medical wards were interviewed. Limited overnight sleep studies were done in 129 of those who had habitual snoring, daytime sleepiness based on an Epworth sleepiness scale of 8 or more, or a large neck size of 40 cm or more. There were 315 Chinese (72.9%), 67 Malays (15.5%), 43 Indians (10%) and 3 from other races (1.4%). The prevalence of OSA was 19.7%, 30% and 12% among the Chinese, Malays and Indians, respectively. The prevalence ratio for OSA was 1.52 in Malays using Chinese patients as the baseline (P = 0.07). The median neck circumference was 37 cm in both racial groups. The median body mass index was 22.7 kg/m2 in Chinese compared to 23.6 kg/m2 in Malays. The median apnoea-hypopnoea index was 22.7, 19.0 and 26.9 events/hour among the Chinese, Malays and Indians, respectively. OSA was independently associated with the prevalence of IHD (adjusted prevalence ratio 1.68; 95% CI: 1.15, 2.46; P = 0.009). The prevalence of ischaemic heart disease (IHD) was 31%, 24% and 28% in Chinese, Malays and Indians, respectively. The prevalence ratio for IHD in Malays compared to Chinese was 0.77. After adjusting for OSA, there was an even greater reduction in the risk of IHD (adjusted prevalence ratio 0.70). This suggests that OSA is a confounder in the relationship between race and ischaemic heart disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0304-4602
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
214-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:10497669-Adult, pubmed-meshheading:10497669-Aged, pubmed-meshheading:10497669-Body Mass Index, pubmed-meshheading:10497669-China, pubmed-meshheading:10497669-Confounding Factors (Epidemiology), pubmed-meshheading:10497669-Ethnic Groups, pubmed-meshheading:10497669-Female, pubmed-meshheading:10497669-Humans, pubmed-meshheading:10497669-India, pubmed-meshheading:10497669-Malaysia, pubmed-meshheading:10497669-Male, pubmed-meshheading:10497669-Middle Aged, pubmed-meshheading:10497669-Myocardial Ischemia, pubmed-meshheading:10497669-Neck, pubmed-meshheading:10497669-Prevalence, pubmed-meshheading:10497669-Risk Factors, pubmed-meshheading:10497669-Singapore, pubmed-meshheading:10497669-Sleep Apnea Syndromes, pubmed-meshheading:10497669-Sleep Stages, pubmed-meshheading:10497669-Snoring
pubmed:year
1999
pubmed:articleTitle
Ethnicity, obstructive sleep apnoea and ischaemic heart disease.
pubmed:affiliation
Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore.
pubmed:publicationType
Journal Article, Comparative Study