Linked Life Data

10497377

Source:http://linkedlifedata.com/resource/pubmed/id/10497377

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1999-11-17
pubmed:abstractText
This study evaluated the effect of the Leukostop filter, a device which reduces the number of leukocytes in blood, on pulmonary function in 15 patients with thalassemia major. Spirometry and oxygen saturation were used to evaluate the influence of filtering the blood. The transfusions consisted of blood which had or had not passed through a Leukostop filter. Blood transfusion induced a significant drop in FEV(1)/FVC ratio in 4 patients, an effect which disappeared following use of the Leukostop filter. Oxygen saturation improved after 6 months of using the Leukostop filter and improved acutely following blood transfusion (both with and without the filter). We conclude that removing most of the leukocytes from the blood during transfusions prevents bronchoconstriction and improves oxygen saturation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
8755-6863
pubmed:author
pubmed:copyrightInfo
Copyright 1999 Wiley-Liss, Inc.
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
277-81
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Effect of the Leukostop filter on pulmonary function following blood transfusion in patients with thalassemia major.
pubmed:affiliation
Institute of Pulmonary and Allergic Diseases, Tel Aviv University, Tel Aviv, Israel.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Controlled Clinical Trial