Source:http://linkedlifedata.com/resource/pubmed/id/10495956
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1999-10-19
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pubmed:abstractText |
Efficiency of heat shock and three compounds belonging to a group of mitotic poisons (colchicine (Cl), griseofulvin (Gf) and vinblastine (Vb)) in induction of dominant lethal mutations (DLM) in the Canton S wild type strain and the l(l)ts403 temperature-sensitive strain was shown. The mutagen-sensitive strain, mus(2)201Gl, displays no sensitivity to these drugs according to the DLM criterion. Heat shock followed by the Vb and Gf treatment leads to a reduction in the frequencies of DLM. Conversely, a combination of Cl with heat shock increases the yield of DLM.
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pubmed:language |
rus
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0016-6758
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
712-5
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:10495956-Animals,
pubmed-meshheading:10495956-Colchicine,
pubmed-meshheading:10495956-Drosophila melanogaster,
pubmed-meshheading:10495956-Embryo, Nonmammalian,
pubmed-meshheading:10495956-Female,
pubmed-meshheading:10495956-Genes, Lethal,
pubmed-meshheading:10495956-Griseofulvin,
pubmed-meshheading:10495956-Hot Temperature,
pubmed-meshheading:10495956-Male,
pubmed-meshheading:10495956-Microtubules,
pubmed-meshheading:10495956-Mitosis,
pubmed-meshheading:10495956-Mutation,
pubmed-meshheading:10495956-Shock,
pubmed-meshheading:10495956-Species Specificity,
pubmed-meshheading:10495956-Vinblastine
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pubmed:year |
1999
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pubmed:articleTitle |
[Frequency of embryonal lethality in various strains of Drosophila melanogaster under conditions of destabilization of microtubule apparatus and as affected by heat shock].
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pubmed:affiliation |
Russian State Pedagogical University, Department of Genetics and Breeding, St. Petersburg, Russia.
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
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