rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1999-10-18
|
pubmed:abstractText |
Chronic treatment with benzodiazepines results in tolerance to their sedative and anxiolytic effects and there is considerable evidence that different mechanisms underlie the development of tolerance to different behavioural effects.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0033-3158
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
145
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
251-9
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:10494573-Animals,
pubmed-meshheading:10494573-Anti-Anxiety Agents,
pubmed-meshheading:10494573-Cerebral Cortex,
pubmed-meshheading:10494573-Diazepam,
pubmed-meshheading:10494573-Drug Tolerance,
pubmed-meshheading:10494573-Hypnotics and Sedatives,
pubmed-meshheading:10494573-Injections, Subcutaneous,
pubmed-meshheading:10494573-Interpersonal Relations,
pubmed-meshheading:10494573-Male,
pubmed-meshheading:10494573-Maze Learning,
pubmed-meshheading:10494573-Motor Activity,
pubmed-meshheading:10494573-Rats,
pubmed-meshheading:10494573-Rats, Sprague-Dawley
|
pubmed:year |
1999
|
pubmed:articleTitle |
The effect of treatment regimen on the development of tolerance to the sedative and anxiolytic effects of diazepam.
|
pubmed:affiliation |
Psychopharmacology Research Unit, GKT School of Biomedical Sciences, King's College London, UK.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|