Linked Life Data

10494163

Source:http://linkedlifedata.com/resource/pubmed/id/10494163

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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1999-10-21
pubmed:abstractText
The aim of the study was to assess an airway function in patients with mitral valve disease at different stages. The study group consisted of 105 consecutive patients with rheumatic mitral valve disease (21-20% pts with mitral stenosis and 84-80% with combined mitral valve disease with a stenosis prevalence). 77 (73%) females, 28 (27%) males, at a mean age 50.4 (28-68) years. Exclusion criteria: aortic valve disease, ischemic left ventricular damage, uncontrolled hypertension, pulmonary and allergic diseases. Each patient was assessed by clinical, echocardiographic, X-ray chest, electrocardiographic examination and airway function studies. An airway obstruction was diagnosed when MEF50 < 60% of predicted value or Raw > 0.3 kPa/lxs-1. To assess airway obstruction reversibility test with fenoterol was performed. In the others nonspecific bronchial provocation test with 0.1% histamine was assessed. Similar number of patients was qualified to II (37%), III (33%) and IV (30%) NYHA functional class. Airway function disturbances were diagnosed in 98 patients (93.5% of all). In most of them airway obstruction was observed (70.5%). Bronchial hyperreactivity was detected in 24 patients (23%). Both airway function disturbances could enhance dyspnoea and fatigue. In the whole study group significant correlations between airway parameters indicating peripheral obstruction or restriction and some cardiological parameters were found. This suggests that peripheral obstruction is proportional to development of a valvular heart disease. Airway resistance which generally represents in 80-90% function of main bronchi was not correlated with any of the analysed cardiological parameters. We conclude that central obstruction is an additional and independent of development of valvular disease part of airway function disturbances.
pubmed:language
pol
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0033-2240
pubmed:author
pubmed:issnType
Print
pubmed:volume
56
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
270-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
[Analysis of airway function in patients with mitral valve disease in various stages of progression].
pubmed:affiliation
I Kliniki Wad Serca.
pubmed:publicationType
Journal Article, Clinical Trial, English Abstract