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rdf:type |
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lifeskim:mentions |
|
|
pubmed:issue |
8
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pubmed:dateCreated |
1999-10-26
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pubmed:abstractText |
High lipoprotein(a) [Lp(a)] plasma concentrations are a genetically determined risk factor for atherosclerotic complications. In healthy subjects Lp(a) concentrations are mostly controlled by the apolipoprotein(a) [apo(a)] gene locus which determines a size polymorphism with more than 30 alleles. Subjects with low molecular weight apo(a) phenotypes on average have higher Lp(a) concentrations than those with high molecular weight apo(a) phenotypes. There are many opinions about whether and why Lp(a) is raised in patients with Type I diabetes (insulin-dependent) mellitus.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0012-186X
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1021-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10491765-Adult,
pubmed-meshheading:10491765-Albuminuria,
pubmed-meshheading:10491765-Apolipoproteins A,
pubmed-meshheading:10491765-Diabetes Mellitus, Type 1,
pubmed-meshheading:10491765-Female,
pubmed-meshheading:10491765-Genetic Predisposition to Disease,
pubmed-meshheading:10491765-Hemoglobin A, Glycosylated,
pubmed-meshheading:10491765-Humans,
pubmed-meshheading:10491765-Lipoprotein(a),
pubmed-meshheading:10491765-Male,
pubmed-meshheading:10491765-Phenotype,
pubmed-meshheading:10491765-Polymorphism, Genetic,
pubmed-meshheading:10491765-Proteinuria,
pubmed-meshheading:10491765-Reference Values,
pubmed-meshheading:10491765-Survivors,
pubmed-meshheading:10491765-Time Factors
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pubmed:year |
1999
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pubmed:articleTitle |
Is apolipoprotein(a) a susceptibility gene for type I diabetes mellitus and related to long-term survival?
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pubmed:affiliation |
Institute of Medical Biology and Human Genetics, University of Innsbruck, Austria.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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