Source:http://linkedlifedata.com/resource/pubmed/id/10488969
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1999-10-13
|
| pubmed:abstractText |
Diminished arterial compliance, or loss of elasticity in large arteries, is an emerging cardiovascular risk factor with a reversible component that includes improved endothelial function. Vitamin E, which may reduce cardiovascular risk, can lower vascular resistance. Twenty-eight middle-aged men and women were randomized through a double-blind design to 8 weeks of supplemental vitamin E (400 IU daily) or placebo. Compliance was determined non-invasively from simultaneous measurements of aortic flow and carotid pressure at baseline and after 4 and 8 weeks. RESULTS: arterial compliance increased by 37% at 4 weeks and by 44% at 8 weeks (P = 0.01) only in the vitamin E group and was independent of an effect on arterial pressure. A rise was seen in 12/14 subjects. There was no significant change with placebo (+ 8%). CONCLUSIONS: short-term vitamin E supplementation improves arterial compliance.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0021-9150
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
145
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
399-404
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:10488969-Adult,
pubmed-meshheading:10488969-Aged,
pubmed-meshheading:10488969-Blood Flow Velocity,
pubmed-meshheading:10488969-Blood Pressure,
pubmed-meshheading:10488969-Cardiovascular Diseases,
pubmed-meshheading:10488969-Carotid Arteries,
pubmed-meshheading:10488969-Diet,
pubmed-meshheading:10488969-Double-Blind Method,
pubmed-meshheading:10488969-Elasticity,
pubmed-meshheading:10488969-Female,
pubmed-meshheading:10488969-Follow-Up Studies,
pubmed-meshheading:10488969-Humans,
pubmed-meshheading:10488969-Lipids,
pubmed-meshheading:10488969-Male,
pubmed-meshheading:10488969-Middle Aged,
pubmed-meshheading:10488969-Questionnaires,
pubmed-meshheading:10488969-Reference Values,
pubmed-meshheading:10488969-Risk Factors,
pubmed-meshheading:10488969-Ultrasonography, Doppler,
pubmed-meshheading:10488969-Vascular Resistance,
pubmed-meshheading:10488969-Vitamin E
|
| pubmed:year |
1999
|
| pubmed:articleTitle |
Vitamin E improves arterial compliance in middle-aged men and women.
|
| pubmed:affiliation |
Baker Medical Research Institute, Melbourne, Australia.
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|