Source:http://linkedlifedata.com/resource/pubmed/id/10487869
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7-8
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pubmed:dateCreated |
1999-12-30
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pubmed:abstractText |
Prediction of gene structure in newly sequenced DNA becomes very important in large genome sequencing projects. This problem is complicated due to the exon-intron structure of eukaryotic genes and because gene expression is regulated by many different short nucleotide domains. In order to be able to analyse the full gene structure in different organisms, it is necessary to combine information about potential functional signals (promoter region, splice sites, start and stop codons, 3' untranslated region) together with the statistical properties of coding sequences (coding potential), information about homologous proteins, ESTs and repeated elements.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1367-4803
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
612-21
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10487869-Amino Acid Sequence,
pubmed-meshheading:10487869-Animals,
pubmed-meshheading:10487869-Base Sequence,
pubmed-meshheading:10487869-Binding Sites,
pubmed-meshheading:10487869-Codon,
pubmed-meshheading:10487869-CpG Islands,
pubmed-meshheading:10487869-DNA,
pubmed-meshheading:10487869-Databases, Factual,
pubmed-meshheading:10487869-Expressed Sequence Tags,
pubmed-meshheading:10487869-Genes,
pubmed-meshheading:10487869-Humans,
pubmed-meshheading:10487869-Internet,
pubmed-meshheading:10487869-Molecular Sequence Data,
pubmed-meshheading:10487869-Sequence Alignment,
pubmed-meshheading:10487869-Software,
pubmed-meshheading:10487869-TATA Box,
pubmed-meshheading:10487869-Transcription Factors,
pubmed-meshheading:10487869-User-Computer Interface
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pubmed:articleTitle |
GeneBuilder: interactive in silico prediction of gene structure.
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pubmed:affiliation |
Istituto di Tecnologie Biomediche Avanzate CNR, via Fratelli Cervi 93, 20090 Segrate, Milano, Italy. milanesi@itba.mi.cnr.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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