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rdf:type |
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lifeskim:mentions |
umls-concept:C0001737,
umls-concept:C0006137,
umls-concept:C0020094,
umls-concept:C0022341,
umls-concept:C0037713,
umls-concept:C0080103,
umls-concept:C0086427,
umls-concept:C0206173,
umls-concept:C0282163,
umls-concept:C0332307,
umls-concept:C1556094
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pubmed:issue |
1
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pubmed:dateCreated |
1999-9-7
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pubmed:databankReference |
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014644,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014645,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014646,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014647,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014648,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014649,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014650,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014651,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014652,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014653,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014654,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014655,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014656,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014657,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014658,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014659,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014660,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014661,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014662,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014663,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014664,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014665,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014666,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014667,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014668,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014669,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF014670
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pubmed:abstractText |
To better understand the origin of human T-cell leukemia virus type l (HTLV-l) in South America, we conducted a phylogenetic study on 27 new HTLV-ls in Brazil. These were obtained from Brazilians of various ethnic origins, such as Japanese immigrants, whites, blacks and mulattos. We amplified and sequenced proviral DNAs of a part of the long terminal repeats. Phylogenetic trees revealed that all but 6 of the new isolates were not only similar to each other but also similar to HTLV-ls of other South American countries, including those from Amerindians. However, the isolates differed from the HTLV-ls of Africa and Japan. The other six isolates were from Japanese immigrants and were phylogenetically almost identical to HTLV-ls in Japan but different from the majority of South American HTLV-ls, including the other new Brazilian HTLV-ls. These findings indicate that the recent introduction of HTLV-1 from Japan is limited to Japanese immigrants. In addition, the results do not support the prevailing hypothesis that HTLV-ls in South America were introduced by blacks who were brought from Africa as slaves. Rather, these results suggest that the majority of HTLV-1s prevailing in South America have spread from Amerindians, some of whom are likely to have possessed this human retrovirus from the beginning of their settlement in South America.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0042-6822
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pubmed:author |
pubmed-author:Andrade-FilhoA SAS,
pubmed-author:BadaroRR,
pubmed-author:BianchiniOO,
pubmed-author:BritesCC,
pubmed-author:ChamoneDD,
pubmed-author:HarringtonW JWJJr,
pubmed-author:HayamiMM,
pubmed-author:IgarashiTT,
pubmed-author:JardimCC,
pubmed-author:Menna-BarretoMM,
pubmed-author:MiuraTT,
pubmed-author:OkhuraSS,
pubmed-author:SampioCC,
pubmed-author:SonodaSS,
pubmed-author:TakehisaJJ,
pubmed-author:VeronesiRR,
pubmed-author:YamashitaMM
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
261
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
59-69
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:10484750-Adult,
pubmed-meshheading:10484750-Africa,
pubmed-meshheading:10484750-Aged,
pubmed-meshheading:10484750-Aged, 80 and over,
pubmed-meshheading:10484750-Base Sequence,
pubmed-meshheading:10484750-Brazil,
pubmed-meshheading:10484750-Emigration and Immigration,
pubmed-meshheading:10484750-Ethnic Groups,
pubmed-meshheading:10484750-Female,
pubmed-meshheading:10484750-HTLV-I Infections,
pubmed-meshheading:10484750-Human T-lymphotropic virus 1,
pubmed-meshheading:10484750-Humans,
pubmed-meshheading:10484750-Japan,
pubmed-meshheading:10484750-Male,
pubmed-meshheading:10484750-Middle Aged,
pubmed-meshheading:10484750-Molecular Epidemiology,
pubmed-meshheading:10484750-Molecular Sequence Data,
pubmed-meshheading:10484750-Phylogeny,
pubmed-meshheading:10484750-Polymerase Chain Reaction,
pubmed-meshheading:10484750-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:10484750-Sequence Analysis, DNA,
pubmed-meshheading:10484750-Terminal Repeat Sequences
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pubmed:year |
1999
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pubmed:articleTitle |
Molecular epidemiology of human T-cell leukemia virus type I (HTLV-1) Brazil: the predominant HTLV-1s in South America differ from HTLV-ls of Japan and Africa, as well as those of Japanese immigrants and their relatives in Brazil.
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pubmed:affiliation |
Laboratory of Viral Pathogenesis, Institute for Virus Research Kyoto University, Kyoto, 606-8507, Japan. myamashi@virus.kyuoto-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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