Source:http://linkedlifedata.com/resource/pubmed/id/10484591
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1999-10-14
|
pubmed:abstractText |
Although there is growing interest in studying muscle distribution, regional skeletal muscle (SM) mass measurement methods remain limited. The aim of the present study was to develop a new dual-energy X-ray absorptiometry (DEXA) model for estimating regional adipose tissue-free skeletal muscle mass (AT-free SM). Relationships were derived from Reference Man data between tissue-system- level components (i.e., AT-free SM, AT, skeleton, and skin) and molecular-level components including fat-free soft tissue, fat, and bone mineral. The proposed DEXA-SM model was evaluated by multiscan computerized axial tomography (CT). Twenty-seven male subjects [age, 36 +/- 12 (SD) yr; body mass, 73.2 +/- 12.4 kg; 20 were healthy, and 7 had acquired immunodeficiency syndrome] completed DEXA and CT studies. Identical landmarks for DEXA and CT measurements were selected in three regions, including calves, thighs, and forearms. There was a strong correlation for AT-free SM estimates between the new DEXA and CT methods (e.g., sum of three regions, r = 0.86, P < 0.001). Regional AT-free SM measured in the 27 subjects by DEXA and CT, respectively, were 3.44 +/- 0.60 and 3. 47 +/- 0.55 kg (difference 0.9%, P > 0.05) for calves, 10.49 +/- 1. 77 and 10.05 +/- 1.79 kg (difference 4.4%, P < 0.05) for thighs, 1. 36 +/- 0.49 and 1.20 +/- 0.41 kg (difference 13.3%, P < 0.01) for forearms, and 15.29 +/- 2.33 and 14.72 +/- 2.33 kg (difference 3.9%, P < 0.05) for the sum all three regions. Although the suggested DEXA-SM model needs minor refinements, this is a promising in vivo approach for measurement of regional SM, because DEXA is widely available, relatively inexpensive, and radiation exposure is low.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
8750-7587
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
87
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1163-71
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:10484591-Absorptiometry, Photon,
pubmed-meshheading:10484591-Adipose Tissue,
pubmed-meshheading:10484591-Adult,
pubmed-meshheading:10484591-Algorithms,
pubmed-meshheading:10484591-Body Composition,
pubmed-meshheading:10484591-Bone Density,
pubmed-meshheading:10484591-Forearm,
pubmed-meshheading:10484591-Humans,
pubmed-meshheading:10484591-Leg,
pubmed-meshheading:10484591-Male,
pubmed-meshheading:10484591-Models, Biological,
pubmed-meshheading:10484591-Muscle, Skeletal,
pubmed-meshheading:10484591-Organ Size,
pubmed-meshheading:10484591-Predictive Value of Tests,
pubmed-meshheading:10484591-Skin,
pubmed-meshheading:10484591-Skinfold Thickness,
pubmed-meshheading:10484591-Tomography, X-Ray Computed
|
pubmed:year |
1999
|
pubmed:articleTitle |
Regional skeletal muscle measurement: evaluation of new dual-energy X-ray absorptiometry model.
|
pubmed:affiliation |
Obesity Research Center, St. Luke's-Roosevelt Hospital, Columbia University, College of Physicians and Surgeons, New York, New York 10025, USA.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.
|