Linked Life Data

10482860

Source:http://linkedlifedata.com/resource/pubmed/id/10482860

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3 Pt 2
pubmed:dateCreated
1999-10-12
pubmed:abstractText
Atopic dermatitis (AD) is a common inflammatory skin disease with increasing prevalence since World War II. Recent studies have shed light on how the complex interrelation of genetic, environmental, immunologic, and pharmacologic factors contributes to the development of AD. The current review will examine the cellular and immunologic mechanisms underlying AD as well as the potential role of microbial superantigens in the pathogenesis of AD. An understanding of the relative contributions of allergens, IgE, T cells with skin homing capability, Langerhans cells, keratinocytes, eosinophils, and mast cells to the inflammatory process in AD may lead to improved treatments for this potentially debilitating disease.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0091-6749
pubmed:author
pubmed:issnType
Print
pubmed:volume
104
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S99-108
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Pathogenesis of atopic dermatitis.
pubmed:affiliation
Division of Pediatric Allergy-Immunology, National Jewish Medical and Research Center, Denver, CO 80206, USA. leungd@njc.org
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review