Source:http://linkedlifedata.com/resource/pubmed/id/10482023
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
1999-10-12
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| pubmed:abstractText |
A prospective analysis of 43 episodes of Pseudomonas aeruginosa bacteremia in HIV-1-infected subjects was performed and the results compared with the incidence and outcome of Pseudomonas aeruginosa bacteremia in other high-risk patients, such as transplant recipients, leukemia patients, or patients hospitalized in the intensive care unit. The incidence of bacteremia/fungemia as a whole and of gram-negative and Pseudomonas aeruginosa bacteremia in particular was greater in HIV-1-infected subjects than in the unselected general population admitted. In contrast, the incidence of Pseudomonas aeruginosa bacteremia in HIV-1-infected patients did not differ from that in patients with other high-risk conditions. In patients with HIV-1 infection, independent risk factors for presenting Pseudomonas aeruginosa bacteremia were nosocomial origin (OR, 2.7; 95% CI, 1.3-5.7), neutropenia (OR, 2.7; 95% CI, 1.07-6.8), previous treatment with cephalosporins (OR, 3.6; 95% CI, 1.1-11.6), and a CD4+ cell count lower than 50 cells/mm3 (OR, 3.1; 95% CI, 1.7-8.6). Primary bacteremia and pneumonia were the most common forms of presentation. Fourteen (33%) patients died as a consequence of the bacteremia. The presence of severe sepsis (OR, 17.5; 95% CI, 3.2-68) and the institution of inappropriate definitive antibiotic therapy (OR, 2.7; 95% CI, 1.1-13) were independently associated with a poor outcome. One year after the development of bacteremia, only eight (19%) patients remained alive.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Jul
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| pubmed:issn |
0934-9723
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
18
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
473-7
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| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:10482023-AIDS-Related Opportunistic Infections,
pubmed-meshheading:10482023-Adolescent,
pubmed-meshheading:10482023-Adult,
pubmed-meshheading:10482023-Aged,
pubmed-meshheading:10482023-Bacteremia,
pubmed-meshheading:10482023-Child,
pubmed-meshheading:10482023-Cohort Studies,
pubmed-meshheading:10482023-Female,
pubmed-meshheading:10482023-HIV-1,
pubmed-meshheading:10482023-Humans,
pubmed-meshheading:10482023-Male,
pubmed-meshheading:10482023-Middle Aged,
pubmed-meshheading:10482023-Outcome Assessment (Health Care),
pubmed-meshheading:10482023-Prospective Studies,
pubmed-meshheading:10482023-Pseudomonas Infections,
pubmed-meshheading:10482023-Pseudomonas aeruginosa,
pubmed-meshheading:10482023-Risk Factors,
pubmed-meshheading:10482023-Spain
|
| pubmed:year |
1999
|
| pubmed:articleTitle |
Pseudomonas aeruginosa bacteremia in patients infected with human immunodeficiency virus type 1.
|
| pubmed:affiliation |
Department of Internal Medicine, Hospital Universitari de Tarragona JOAN XXIII, Faculty of Medicine and Health Sciences, University Rovira i Virgili, Tarragona, Spain. fvidal@galenics.com
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|