Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1999-9-30
pubmed:abstractText
The eponym Sister (Mary) Joseph's nodule is referred to the existence of umbilical metastasis. Historically it has been considered a sign of ominous vital prognosis and therapeutic abstention. The analysis of 407 cases published at the medical literature (MEDLINE 1966-1997) is against this idea, because recent series have showed survivals longer than a year after treatment. On the other hand 60% of umbilical nodules are benign. Nowadays this sign must be considered as an early indicator of inner neoplasms, mainly from the abdominal cavity (52% digestive origin, 28% gynecologic origin), and in 40% of cases they are the only expression of relapse of previously known neoplasms. When a umbilical nodule is found it is necessary to make an accurate histologic differential diagnosis between a primary (benign or neoplastic) and metastatic lesions. Fine needle aspiration has demonstrated to be an easy and reliable method for diagnosis. Once the metastatic origin of the nodule is confirmed treatment with curative intention must be tried.
pubmed:language
spa
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0212-7199
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
365-70
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
[Sister Mary Joseph's nodule. Its clinical significance and management].
pubmed:affiliation
Servicio de Medicina Interna General, Hospital Clínic i Provincial, Universidad de Barcelona.
pubmed:publicationType
Journal Article, English Abstract, Review