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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1999-11-8
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pubmed:abstractText |
Lipopolysaccharide was injected into germ-free mice after they had been infected with Vero toxin-producing Escherichia coli. Microscopic examination of the kidneys of these mice showed an increased number of mesangial cells and a vacancy in the glomerular capillary lumen. A significant elevation in the expression level of interferon (IFN)-gamma in the kidney may have played a key role in the induction of glomerular lesions, because the administration of neutralizing antibody to IFN-gamma markedly alleviated such lesions.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0022-1899
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
180
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1374-7
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:10479176-Animals,
pubmed-meshheading:10479176-Bacterial Toxins,
pubmed-meshheading:10479176-Capillaries,
pubmed-meshheading:10479176-Escherichia coli,
pubmed-meshheading:10479176-Escherichia coli Infections,
pubmed-meshheading:10479176-Germ-Free Life,
pubmed-meshheading:10479176-Glomerular Mesangium,
pubmed-meshheading:10479176-Interferon-gamma,
pubmed-meshheading:10479176-Kidney Glomerulus,
pubmed-meshheading:10479176-Lipopolysaccharides,
pubmed-meshheading:10479176-Male,
pubmed-meshheading:10479176-Mice,
pubmed-meshheading:10479176-Mice, Inbred BALB C,
pubmed-meshheading:10479176-Shiga Toxin 1
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pubmed:year |
1999
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pubmed:articleTitle |
Induction of glomerular lesions in the kidneys of mice infected with vero toxin-producing Escherichia coli by lipopolysaccharide injection.
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pubmed:affiliation |
Department of Nursing, Tokai University School of Health Sciences, Isehara, Japan.
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pubmed:publicationType |
Journal Article
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