| pubmed-article:10476732 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10476732 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:10476732 | lifeskim:mentions | umls-concept:C0006948 | lld:lifeskim |
| pubmed-article:10476732 | lifeskim:mentions | umls-concept:C0013502 | lld:lifeskim |
| pubmed-article:10476732 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:10476732 | lifeskim:mentions | umls-concept:C0332293 | lld:lifeskim |
| pubmed-article:10476732 | lifeskim:mentions | umls-concept:C0443252 | lld:lifeskim |
| pubmed-article:10476732 | lifeskim:mentions | umls-concept:C0053183 | lld:lifeskim |
| pubmed-article:10476732 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:10476732 | pubmed:dateCreated | 1999-12-2 | lld:pubmed |
| pubmed-article:10476732 | pubmed:abstractText | Four hundred forty-eight patients with 929 Echinococcus granulosus hydatid cysts received 3- to 6-month continuous cycles of mebendazole or albendazole treatment and underwent prolonged follow-up by clinical visits and imaging studies (range, 1-14 years) to assess the long-term outcome of treatment. Degenerative changes and relapse were assessed by imaging techniques. At the end of therapy, 74.1% of the hydatid cysts showed degenerative changes. These were more frequent in albendazole-treated than in mebendazole-treated cysts (82.2% vs. 56.1%; P < .001). During long-term follow-up, 104 cysts (22%) had degenerative changes that progressed, whereas 163 cysts (approximately 25%) relapsed. The percentages of relapses in the two drug-treated groups were almost the same. Relapses occurred more frequently in type II cysts of the liver. Cysts recurred most often (78.5%; P < .001) within the first 2 years after treatment ended. Further chemotherapy cycles induced degenerative changes in >90% of relapsed cysts without inducing more frequent or more severe side effects than those observed during the initial cycles. | lld:pubmed |
| pubmed-article:10476732 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10476732 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10476732 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10476732 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:10476732 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10476732 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:10476732 | pubmed:issn | 1058-4838 | lld:pubmed |
| pubmed-article:10476732 | pubmed:author | pubmed-author:TeggiAA | lld:pubmed |
| pubmed-article:10476732 | pubmed:author | pubmed-author:FrancheOO | lld:pubmed |
| pubmed-article:10476732 | pubmed:author | pubmed-author:Di VicoBB | lld:pubmed |
| pubmed-article:10476732 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10476732 | pubmed:volume | 29 | lld:pubmed |
| pubmed-article:10476732 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10476732 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10476732 | pubmed:pagination | 304-9 | lld:pubmed |
| pubmed-article:10476732 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:10476732 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10476732 | pubmed:articleTitle | Long-term evaluation of patients with hydatidosis treated with benzimidazole carbamates. | lld:pubmed |
| pubmed-article:10476732 | pubmed:affiliation | Department of Infectious and Tropical Diseases, University of Rome La Sapienza, Italy. | lld:pubmed |
| pubmed-article:10476732 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10476732 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:10476732 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| pubmed-article:10476732 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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