Source:http://linkedlifedata.com/resource/pubmed/id/10474223
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6-7
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pubmed:dateCreated |
1999-9-30
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pubmed:abstractText |
Important chemical and biochemical properties of boranophosphate DNA and RNA oligonucleotides are reviewed. Stereoregular boranophosphate oligomers can be synthesized enzymatically and form stable duplexes with DNA. Fully boronated, non-stereoregular oligothymidylates, synthesized chemically, form hybrids with poly(A) that have lower melting points than oligothymidylate:poly(A), yet they nevertheless can support the RNase H mediated cleavage of RNA.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0732-8311
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1379-80
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading | |
pubmed:articleTitle |
Boranophosphate nucleic acids--a versatile DNA backbone.
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pubmed:affiliation |
Department of Chemistry, Duke University, Durham, NC 27708-0346, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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