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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
1999-9-21
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pubmed:abstractText |
Malignant pericardial effusion is usually treated only when signs of cardiac tamponade develop. Several methods of treatment have been reported with an overall response rate of approximately 75%. Since our initial study using intrapericardial 32P-colloid instillation as a treatment modality for pericardial effusion demonstrated a significant higher response rate, this study was conducted to further evaluate the efficacy of intrapericardial 32P-colloid in terms of response rates and duration of remissions. Intrapericardial instillation of 185-370 MBq (5-10 mCi) 32P-colloid in 36 patients with malignant pericardial effusion resulted in a complete remission rate of 94.5% (34 patients) whereas two patients did not respond to treatment due to a foudroyant formation of pericardial fluid. The median duration time was 8 months. No side-effects were observed. These results suggest that intrapericardial instillation of 32P-colloid is a simple, reliable and safe treatment strategy for patients with malignant pericardial effusions. Therefore, since further evidence is provided that 32P-colloid is significantly more effective than external radiation or non-radioactive sclerosing agents, this treatment modality should be considered for the management of malignant pericardial effusion.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/10471044-1118576,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10471044-13016041,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10471044-14930202,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10471044-1555467,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10471044-2480244,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10471044-2681217,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10471044-3594362,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10471044-3951784,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10471044-403795,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10471044-4067615,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10471044-4192038,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10471044-4272474,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10471044-7007942,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10471044-763235,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10471044-9667253
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0007-0920
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
80
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1955-7
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:10471044-Breast Neoplasms,
pubmed-meshheading:10471044-Cardiac Tamponade,
pubmed-meshheading:10471044-Chromium Compounds,
pubmed-meshheading:10471044-Female,
pubmed-meshheading:10471044-Gastrointestinal Neoplasms,
pubmed-meshheading:10471044-Humans,
pubmed-meshheading:10471044-Instillation, Drug,
pubmed-meshheading:10471044-Lung Neoplasms,
pubmed-meshheading:10471044-Lymphoma,
pubmed-meshheading:10471044-Neoplasms,
pubmed-meshheading:10471044-Pericardial Effusion,
pubmed-meshheading:10471044-Phosphorus Radioisotopes,
pubmed-meshheading:10471044-Radiopharmaceuticals
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pubmed:year |
1999
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pubmed:articleTitle |
Treatment of malignant pericardial effusion with 32P-colloid.
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pubmed:affiliation |
Martin-Luther-University Halle-Wittenberg, Department of Internal Medicine IV, Halle, Germany.
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pubmed:publicationType |
Journal Article,
Clinical Trial
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