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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1999-9-10
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pubmed:abstractText |
Oxyhemoglobin (OxyHb) is one of the most important spasmogens for cerebral vasospasm that follows aneurysmal subarachnoid hemorrhage. The cytotoxic effect of OxyHb has been documented in endothelial and smooth-muscle cells; however, the pattern of cell death--necrosis or apoptosis--as the final stage of cell damage has not been demonstrated. This study was undertaken to determine if OxyHb induces apoptotic changes in cultured bovine aortic endothelial cells.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0022-3085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
459-65
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:10470822-Animals,
pubmed-meshheading:10470822-Aorta,
pubmed-meshheading:10470822-Apoptosis,
pubmed-meshheading:10470822-Blotting, Western,
pubmed-meshheading:10470822-Cattle,
pubmed-meshheading:10470822-Cell Count,
pubmed-meshheading:10470822-Cell Death,
pubmed-meshheading:10470822-Cell Nucleus,
pubmed-meshheading:10470822-Cells, Cultured,
pubmed-meshheading:10470822-Clone Cells,
pubmed-meshheading:10470822-DNA Fragmentation,
pubmed-meshheading:10470822-Dose-Response Relationship, Drug,
pubmed-meshheading:10470822-Electrophoresis, Agar Gel,
pubmed-meshheading:10470822-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:10470822-Endothelium, Vascular,
pubmed-meshheading:10470822-Intracranial Aneurysm,
pubmed-meshheading:10470822-Ischemic Attack, Transient,
pubmed-meshheading:10470822-Luminescent Measurements,
pubmed-meshheading:10470822-Microscopy, Electron,
pubmed-meshheading:10470822-Muscle, Smooth, Vascular,
pubmed-meshheading:10470822-Necrosis,
pubmed-meshheading:10470822-Nucleosomes,
pubmed-meshheading:10470822-Oxyhemoglobins,
pubmed-meshheading:10470822-Poly(ADP-ribose) Polymerases,
pubmed-meshheading:10470822-Subarachnoid Hemorrhage,
pubmed-meshheading:10470822-Time Factors
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pubmed:year |
1999
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pubmed:articleTitle |
Oxyhemoglobin-induced apoptosis in cultured endothelial cells.
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pubmed:affiliation |
Department of Neurosurgery, University of Mississippi Medical Center, Jackson 39216, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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