Source:http://linkedlifedata.com/resource/pubmed/id/10470233
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4A
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pubmed:dateCreated |
1999-9-28
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pubmed:abstractText |
This paper describes an automated immunoassay for the measurement of TPS developed for the IMMULITE. The IMMULITE system is a fully automated continous random access analyzer, which uses enzyme-amplified chemiluminiscent as the detection system. The IMMULITE TPS assay is a sequential, two-site chemiluminiscent enzyme immunometric assay designed for the quantitative measurement of TPS in serum. The IMMULITE TPS assay covers a clinical concentration range of 20-2400 U/L, with a lower detection limit of 6 U/L. A serum method comparison (n = 340) to the TPS IRMA assay demonstrates a correlation coefficient of 0.961 and a slope of 1.04. Samples run on IMMULITE TPS assay exhibit linearity upon dilution where recovered values fall within 15% of the theoretical sample value. The intra-assay precision of the IMMULITE TPS assay ranged from 3.3-4.7%, while the interassay precision ranged from 3.9-6.0%. By using different methods (immunoradiometric assay vs chemiluminiscent enzyme-labeled immunometric assay, one-step procedure vs sequential two-step procedure, manual vs fully automated procedure) the two TPS tumor marker tests used in this study gave quite comparable determinations for the sera from the cancer patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Carcinoembryonic Antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological,
http://linkedlifedata.com/resource/pubmed/chemical/tissue polypeptide specific antigen
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pubmed:status |
MEDLINE
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pubmed:issn |
0250-7005
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2743-7
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:10470233-Antibodies, Monoclonal,
pubmed-meshheading:10470233-Autoanalysis,
pubmed-meshheading:10470233-Breast Neoplasms,
pubmed-meshheading:10470233-Calibration,
pubmed-meshheading:10470233-Carcinoembryonic Antigen,
pubmed-meshheading:10470233-Colonic Neoplasms,
pubmed-meshheading:10470233-Female,
pubmed-meshheading:10470233-Humans,
pubmed-meshheading:10470233-Immunoassay,
pubmed-meshheading:10470233-Immunoradiometric Assay,
pubmed-meshheading:10470233-Luminescent Measurements,
pubmed-meshheading:10470233-Peptides,
pubmed-meshheading:10470233-Regression Analysis,
pubmed-meshheading:10470233-Reproducibility of Results,
pubmed-meshheading:10470233-Sensitivity and Specificity,
pubmed-meshheading:10470233-Time Factors,
pubmed-meshheading:10470233-Tumor Markers, Biological
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pubmed:articleTitle |
Performance characteristics of IMMULITE TPS: a comparison with TPS IRMA.
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pubmed:affiliation |
BEKI Diagnostics, Bromma, Stockholm, Sweden.
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pubmed:publicationType |
Journal Article,
Comparative Study
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