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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3A
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pubmed:dateCreated |
1999-9-20
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pubmed:abstractText |
Cervical cancer constitutes the second most common cancer in women. Estrogen promotes development of cervical cancer in cells infected with high risk human papillomaviruses (HPVs). We asked whether the phytochemical indole-3-carbinol (I3C) has anti-estrogenic activities in cervical cells with the goal of preventing cancer in HPV infected cells.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/2-hydroxyestrone,
http://linkedlifedata.com/resource/pubmed/chemical/Anticarcinogenic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP1A1,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP1A2,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 Enzyme System,
http://linkedlifedata.com/resource/pubmed/chemical/E6 protein, Human papillomavirus...,
http://linkedlifedata.com/resource/pubmed/chemical/Estradiol,
http://linkedlifedata.com/resource/pubmed/chemical/Estrogen Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Hydroxyestrones,
http://linkedlifedata.com/resource/pubmed/chemical/Indoles,
http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Oncogene Proteins, Viral,
http://linkedlifedata.com/resource/pubmed/chemical/Papillomavirus E7 Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Viral,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Estrogen,
http://linkedlifedata.com/resource/pubmed/chemical/Repressor Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/indole-3-carbinol,
http://linkedlifedata.com/resource/pubmed/chemical/oncogene protein E7, Human...
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pubmed:status |
MEDLINE
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pubmed:issn |
0250-7005
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1673-80
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:10470100-Anticarcinogenic Agents,
pubmed-meshheading:10470100-Binding, Competitive,
pubmed-meshheading:10470100-Carcinoma, Squamous Cell,
pubmed-meshheading:10470100-Cervix Uteri,
pubmed-meshheading:10470100-Cytochrome P-450 CYP1A1,
pubmed-meshheading:10470100-Cytochrome P-450 CYP1A2,
pubmed-meshheading:10470100-Cytochrome P-450 Enzyme System,
pubmed-meshheading:10470100-Enzyme Induction,
pubmed-meshheading:10470100-Estradiol,
pubmed-meshheading:10470100-Estrogen Antagonists,
pubmed-meshheading:10470100-Female,
pubmed-meshheading:10470100-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:10470100-Gene Expression Regulation, Viral,
pubmed-meshheading:10470100-Humans,
pubmed-meshheading:10470100-Hydroxyestrones,
pubmed-meshheading:10470100-Indoles,
pubmed-meshheading:10470100-Neoplasm Proteins,
pubmed-meshheading:10470100-Oncogene Proteins, Viral,
pubmed-meshheading:10470100-Oncogenes,
pubmed-meshheading:10470100-Papillomaviridae,
pubmed-meshheading:10470100-Papillomavirus E7 Proteins,
pubmed-meshheading:10470100-Papillomavirus Infections,
pubmed-meshheading:10470100-RNA, Messenger,
pubmed-meshheading:10470100-RNA, Neoplasm,
pubmed-meshheading:10470100-RNA, Viral,
pubmed-meshheading:10470100-Receptors, Estrogen,
pubmed-meshheading:10470100-Repressor Proteins,
pubmed-meshheading:10470100-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:10470100-Tumor Cells, Cultured,
pubmed-meshheading:10470100-Tumor Virus Infections,
pubmed-meshheading:10470100-Uterine Cervical Neoplasms
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pubmed:articleTitle |
Anti-estrogenic activities of indole-3-carbinol in cervical cells: implication for prevention of cervical cancer.
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pubmed:affiliation |
Long Island Jewish Medical Center, Albert Einstein College of Medicine, Department of Otolaryngology, New Hyde Park, NY 11040, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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