Source:http://linkedlifedata.com/resource/pubmed/id/10469038
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1999-11-9
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pubmed:abstractText |
Atopy is a genetically determined condition and some atopic people develop airway hyperresponsiveness and sometimes asthma later in life. Since airway inflammation may be present before the onset of clinical symptoms of asthma, early and noninvasive detection of inflammation would be useful in atopic subjects. Mediators produced by activated inflammatory cells may lead to induction of inducible nitric oxide synthase producing nitric oxide (NO) and inducible heme oxygenase releasing carbon monoxide (CO) in the airways. Both monoxides are present in exhaled air and their levels are elevated in asthma reflecting airway inflammation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0954-7894
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1276-80
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10469038-Adolescent,
pubmed-meshheading:10469038-Adult,
pubmed-meshheading:10469038-Breath Tests,
pubmed-meshheading:10469038-Bronchoconstrictor Agents,
pubmed-meshheading:10469038-Carbon Monoxide,
pubmed-meshheading:10469038-Female,
pubmed-meshheading:10469038-Humans,
pubmed-meshheading:10469038-Hypersensitivity, Immediate,
pubmed-meshheading:10469038-Inflammation,
pubmed-meshheading:10469038-Male,
pubmed-meshheading:10469038-Methacholine Chloride,
pubmed-meshheading:10469038-Nitric Oxide,
pubmed-meshheading:10469038-Respiratory Function Tests
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pubmed:year |
1999
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pubmed:articleTitle |
Exhaled monoxides in asymptomatic atopic subjects.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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