rdf:type |
|
lifeskim:mentions |
umls-concept:C0001527,
umls-concept:C0002844,
umls-concept:C0014442,
umls-concept:C0017262,
umls-concept:C0025663,
umls-concept:C0185117,
umls-concept:C0205345,
umls-concept:C0599161,
umls-concept:C0679932,
umls-concept:C1421338,
umls-concept:C1517025,
umls-concept:C2911684
|
pubmed:issue |
5
|
pubmed:dateCreated |
1999-10-4
|
pubmed:abstractText |
We have demonstrated previously that obesity in men was significantly associated with low plasma testosterone levels and higher concentrations of the androgen metabolite androstane-3 alpha, 17 beta-diol glucuronide, suggesting that androgen metabolism and elimination is increased in this condition. The objective of the present study was to investigate whether adipose tissue was a site of expression of the androgen metabolizing enzymes UDP-glucuronosyltransferases (UGT) 2B15 and 2B17.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0300-0664
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
50
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
637-42
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:10468930-Adipose Tissue,
pubmed-meshheading:10468930-Adult,
pubmed-meshheading:10468930-Aged,
pubmed-meshheading:10468930-Androgens,
pubmed-meshheading:10468930-Breast,
pubmed-meshheading:10468930-Glucuronosyltransferase,
pubmed-meshheading:10468930-Humans,
pubmed-meshheading:10468930-Kidney,
pubmed-meshheading:10468930-Liver,
pubmed-meshheading:10468930-Lung,
pubmed-meshheading:10468930-Male,
pubmed-meshheading:10468930-Middle Aged,
pubmed-meshheading:10468930-Obesity,
pubmed-meshheading:10468930-Prostate,
pubmed-meshheading:10468930-RNA, Messenger,
pubmed-meshheading:10468930-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:10468930-Testis
|
pubmed:year |
1999
|
pubmed:articleTitle |
Expression of the androgen metabolizing enzyme UGT2B15 in adipose tissue and relative expression measurement using a competitive RT-PCR method.
|
pubmed:affiliation |
Molecular Endocrinology Laboratory, CHUQ Research Center, Ste-Foy, Québec, Canada.
|
pubmed:publicationType |
Journal Article
|